Mouse Anti-TF Recombinant Antibody (clone JAA-F11); Fab Fragment (CAT#: PFBW-164)
Recombinant Mouse Antibody (JAA-F11) Fab Fragment is specific to TF antigen(Galβ1-3GalNAcα), expressed in Chinese Hamster Ovary cells (CHO). JAA-F11 preferentially binds to tumor tissue over normal, and in vivo it enhances survival and decreases metastasis in the mouse 4T1 metastatic model, indicating a potential for this mAb to be used, after humanization, in cancer patient therapy.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Liver
(Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_4.jpg
(Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_4.jpg
Figure 2 Kidney
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_5.jpg
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_5.jpg
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000091513-TF
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000091513-TF
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091513-TF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091513-TF
Specifications
- Immunogen
- Human Thomsen-Friedenreich antigen (Galβ1-3GalNAcα)
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human TF
- Species Reactivity
- Human
- Clone
- JAA-F11
- Applications
- FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Galβ1-3GalNAcα; Thomsen-Friedenreich; TF
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-343 | Mouse Anti-TF Recombinant Antibody (clone 6A6); Fab Fragment | WB, ELISA, IF, FuncS | Mouse Fab |
| HPAB-0767-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0767-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0768-CN-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0768-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-M0321-YC-F(E) | Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-M0321-YC-F(E)) | ELISA, Inhib | Chimeric (Mouse/Human) Fab |
| HPAB-1276WJ-F(E) | Mouse Anti-TF Recombinant Antibody; Fab Fragment (HPAB-1276WJ-F(E)) | ELISA | Mouse Fab |
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