Mouse Anti-TF Recombinant Antibody (clone JAA-F11); scFv Fragment

CAT#: PSBW-164

Recombinant Mouse Antibody (JAA-F11) scFv Fragment is specific to TF antigen(Galβ1-3GalNAcα), expressed in E. coli. JAA-F11 preferentially binds to tumor tissue over normal, and in vivo it enhances survival and decreases metastasis in the mouse 4T1 metastatic model, indicating a potential for this mAb to be used, after humanization, in cancer patient therapy.

Tested Data Gene Expression
Figure 1 Mouse Anti-TF Recombinant Antibody; scFv Fragment (PSBW-164) in SDS-PAGE
Figure 1 Liver Figure 2 Kidney Figure 3 RNA cell line category: Cell line enriched (Hep G2) Figure 3 RNA cell line category: Cell line enriched (Hep G2)

Specifications

  • Immunogen
  • Human Thomsen-Friedenreich antigen (Galβ1-3GalNAcα)
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human TF
  • Species Reactivity
  • Human
  • Clone
  • JAA-F11
  • Applications
  • FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Galβ1-3GalNAcα; Thomsen-Friedenreich; TF
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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COA

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