Human Anti-TF Recombinant Antibody (clone hATR-5) (CAT#: PABC-122)
Recombinant Humanized Antibody (hATR-5) is capable of binding to TF, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TF mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TF mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody strongly inhibits TF-initiated blood coagulation, and is of potential use for various thrombotic diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 Liver
(Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_4.jpg
(Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_4.jpg
Figure 2 Kidney
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_5.jpg
(Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_5.jpg
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000091513-TF
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000091513-TF
Figure 3 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091513-TF
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091513-TF
Specifications
- Immunogen
- Human coagulation factor III (thromboplastin, tissue factor)
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human TF
- Species Reactivity
- Human
- Clone
- hATR-5
- Applications
- Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor
- Gene ID
- 2152
- UniProt ID
- P13726
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-343 | Mouse Anti-TF Recombinant Antibody (clone 6A6); scFv Fragment | WB, ELISA, IF, FuncS | Mouse scFv |
| HPAB-0232-YJ-S(P) | Rat Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0232-YJ-S(P)) | ELISA, FuncS | Rat scFv |
| HPAB-0233-YJ-S(P) | Rat Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0233-YJ-S(P)) | ELISA, FC, FuncS | Rat scFv |
| HPAB-M0321-YC-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-M0321-YC-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-0717YY-S(P) | Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0717YY-S(P)) | ELISA, Inhib, WB, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
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