This immunotoxin was achieved by conjugating/fusing the Anti-TFRC scFv to gelonin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then, gelonin, like abrin and ricin, inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes. It was designed for treating malignant.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G067E | Anti-TFRC immunotoxin HB21 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G067D | Anti-TFRC immunotoxin HB21 (scFv)-DT | Cytotoxicity assay, Function study | |
AGTO-G067R | Anti-TFRC immunotoxin HB21 (scFv)-RTA | Cytotoxicity assay, Function study | |
AGTO-G067S | Anti-TFRC immunotoxin HB21 (scFv)-Sap | Cytotoxicity assay, Function study | |
AGTO-G068E | Anti-TFRC immunotoxin 454A12 (IgG)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0464CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0464CL) | FuncS | Mouse IgG |
TAB-615CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (6-90) | ELISA, WB, IP | |
TAB-616CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (55-31) | ELISA, WB, IP | |
TAB-617CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (122-72) | ELISA, WB, IP | |
TAB-618CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (5D7-54.17) | ELISA, WB, IP |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-619CT | Human Anti-TFRC Recombinant Antibody (TAB-619CT) | ELISA, WB | Human antibody |
TAB-620CT | Human Anti-TFRC Recombinant Antibody (TAB-620CT) | ELISA, WB | Human antibody |
TAB-621CT | Anti-Human TfR Recombinant Antibody (LUCA31) | ELISA, WB, FC | Human antibody |
TAB-623CT | Anti-Human TfR Recombinant Antibody (3TF12) | WB | Human antibody |
TAB-624CT | Anti-Human TfR Recombinant Antibody (3TF2) | WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-611CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-611CT-S(P)) | ELISA | Humanized scFv |
TAB-612CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-612CT-S(P)) | ELISA | Humanized scFv |
TAB-613CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-613CT-S(P)) | ELISA | Humanized scFv |
TAB-614CT-S(P) | Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-614CT-S(P)) | ELISA | Humanized scFv |
TAB-611CT-F(E) | Humanized Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-611CT-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1999CQ | Rat Anti-Tfrc Recombinant Antibody (clone RI7217) | FC, ICC, IP, WB, Block | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3548 | Rabbit Anti-TFRC Recombinant Antibody (clone DS3548AB) | FC, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC3370 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTGKL) MHC Tetramer | FCM | |
MHC-LC3371 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTG) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0376-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0376-CN) | ELISA, FC | Mouse IgG |
HPAB-0377-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0377-CN) | ELISA, FC | Mouse IgG |
HPAB-0378-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0378-CN) | ELISA, FC | Mouse IgG |
HPAB-0379-CN | Human Anti-TFRC Recombinant Antibody (HPAB-0379-CN) | ELISA, FC | Humanized IgG |
HPAB-0380-CN | Mouse Anti-TFRC Recombinant Antibody (clone BA120G) | ELISA, FC, IF, IP | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0376-CN-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0376-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0377-CN-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0377-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0378-CN-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0378-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0379-CN-F(E) | Human Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0379-CN-F(E)) | ELISA, FC | Humanized Fab |
HPAB-0380-CN-F(E) | Mouse Anti-TFRC Recombinant Antibody (clone BA120G); Fab Fragment | ELISA, FC, IF, IP | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0281-YC-S(P) | Mouse Anti-TFRC Recombinant Antibody (clone OX26); scFv Fragment | ELISA | Mouse scFv |
HPAB-597-FY-S(P) | Human Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-597-FY-S(P)) | ELISA | Humanized scFv |
HPAB-0238-YJ-S(P) | Rat Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0238-YJ-S(P)) | IHC, FC, WB, FuncS | Rat scFv |
HPAB-2624LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2624LY-S(P)) | ELISA | Mouse scFv |
HPAB-2707LY-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-2707LY-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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