1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Anti-TFRC immunotoxin HB21 (scFv)-Gel (CAT#: AGTO-G067G)

    This immunotoxin was achieved by conjugating/fusing the Anti-TFRC scFv to gelonin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then, gelonin, like abrin and ricin, inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes. It was designed for treating malignant.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to endosomes & lysosomes.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28598/546_F8_1_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/207_B2_1_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/208_B2_1_blue_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Glandular cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_3.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining:

    Medium

    Intensity: Strong
    Quantity: <25%
    Pachytene spermatocytes
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_6_6.jpg
    Figure 7 Bone marrow
    Figure 7 Bone marrow
    (Hematopoietic cells
    Staining:

    High

    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_6_4.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Germinal center cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000072274-TFRC
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072274-TFRC

    Specifications

    • Host Species
    • Mouse
    • Species Reactivity
    • Human
    • Clone
    • HB21
    • Molecule Class
    • scFv-Gel
    • Toxin Description
    • Gelonin is a glycoprotein (M.W. approximately 29-30,000 Kd) purified from the seeds of Gelonium multiforum and belongs to a class of potent ribosomal-inactivating plant toxins. Gelonin, like abrin and ricin, inhibits protein synthesis by damaging the 60S subunit of mammalian ribosomes.
    • Applications
    • This product is suitable for use in cytotoxicity assay, functional assay and immunotherapy.
    • Related Disease
    • malignant

    Target

    • Alternative Names
    • TFRC; transferrin receptor; T9; TR; TFR; p90; CD71; TFR1; TRFR; transferrin receptor protein 1; transferrin receptor (p90, CD71); Gelonin; Gel

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone HB21"

    See other products for "TFRC"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Fab Antibody Products ScFv Antibody Products Immunotoxin Products Mouse Antibody Products Human Antibody Products Humanized Antibody Products IgM Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products MHC Tetramer Products for Cancer Antibody Magnetic Beads Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1176z Mouse Anti-TFRC Recombinant Antibody (MOB-1176z) ELISA, WB, IP, IF, IHC, FC Mouse IgG1, κ
    MOB-035LC Rat Anti-TFRC Recombinant Antibody (clone 9E4) FuncS, IHC, FC Rat IgG
    HPAB-0238-YJ Rat Anti-TFRC Recombinant Antibody (HPAB-0238-YJ) IHC, FC, WB, FuncS Rat IgG2a
    HPAB-0239-YJ Mouse Anti-TFRC Recombinant Antibody (HPAB-0239-YJ) IHC, FC, WB, FuncS Chimeric (mouse/rat) IgG1, κ
    VS-0723-WK21 Human Anti-TFRC Recombinant Antibody (clone Pabinafusp Alfa) FC Human IgG1

    Customer Reviews and Q&As

    Submit a review or a question

    There are currently no Customer reviews or questions for AGTO-G067G. Click the button above to contact us or submit your feedback about this product.

    Popular products with customers

    Figure 5 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in ELISA

    Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) (CAT# TAB-709)
    Application: IF, IP, Neut, FuncS, ELISA, FC, WB

    Figure 2 Anti-Human CD3 Antibody (TAB-159) in FC

    Anti-Human CD3 Recombinant Antibody (TAB-159) (CAT# TAB-159)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 3 Anti-CD40 Antibody (TAB-152) in Dot Blot

    Anti-Human CD40 Recombinant Antibody (TAB-152) (CAT# TAB-152)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 2 CD276 Recombinant Antibody (TAB-117CL) in HPLC

    Anti-Human CD276 Recombinant Antibody (TAB-117CL) (CAT# TAB-117CL)
    Application: ADCC, FuncS

    Figure 2 Anti-Human SLAMF7 Recombinant Antibody (TAB-570CL) in ELISA

    Human Anti-SLAMF7 Recombinant Antibody (TAB-570CL) (CAT# TAB-570CL)
    Application: IF, IHC, Inhib

    Figure 1 Recombinant Human Anti-DENV E proteins Antibody (PABL-067) in SDS-PAGE

    Recombinant Human Anti-DENV E proteins Antibody (5J7) (CAT# PABL-067)
    Application: ELISA, Neut, FuncS

    Figure 2 Human Anti-VEGF Recombinant Antibody (PABC-131) in ELISA

    Human Anti-VEGF Recombinant Antibody (clone B20-4) (CAT# PABC-131)
    Application: ELISA, Neut, Block

    Figure 2 Recombinant Anti-VEEV E2 Antibody (PABL-742) in HPLC

    Recombinant Human Anti-VEEV E2 Antibody (3B4C-4) (CAT# PABL-742)
    Application: Neut

    Figure 1 Anti-CD3 Antibody (TAB-0416CL) Induced PBMCs Proliferation

    Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (CAT# TAB-0416CL)
    Application: FC, IB, ELISA

    Figure 2 Anti-Human CLDN6 Recombinant Antibody (TAB-510LC) in HPLC

    Mouse Anti-CLDN6 Recombinant Antibody (TAB-510LC) (CAT# TAB-510LC)
    Application: Cyt, FC, FuncS

    Figure 5 Human Anti-SLC34A2 Recombinant Antibody (TAB-468MZ) in DB

    Human Anti-SLC34A2 Recombinant Antibody (TAB-468MZ) (CAT# TAB-468MZ)
    Application: FC, Inhib

    Figure 2 Anti-CD5 Antibody (53-7.3) Fab Fragment (NEUT-392CQ-Fab) in ELISA

    Rat Anti-CD5 Recombinant Antibody (clone 53-7.3) (CAT# NEUT-392CQ)
    Application: FC, IHC-Fr, IP, ELISA, Block

    Figure 3 Anti-Human CD274 Antibody (TAB-417CQ) in DB

    Anti-Human CD274 Recombinant Antibody (TAB-417CQ) (CAT# TAB-417CQ)
    Application: ELISA, IHC, FC, IP, IF, Inhib

    Figure 3 Anti-Human IAV HA Recombinant Antibody (MOB-074LC) in ELISA

    Human Anti-EPCAM Recombinant Antibody (clone ING-1) (CAT# MOB-074LC)
    Application: ELISA, FuncS

    Figure 3 Anti-LAM Recombinant Fab Fragment Antibody (PFBC-542) in WB

    Recombinant Human Anti-LAM Antibody Fab Fragment (PFBC-542) (CAT# PFBC-542)
    Application: ELISA, WB

    Figure 3 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in Lectin ELISA

    Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) (CAT# AFC-TAB-071)
    Application: Neut, ELISA, IF, IP, FuncS, FC

    Figure 2 Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) in HPLC

    Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) (CAT# HPAB-N0094-YC)
    Application: Neut, WB

    Figure 2 Recombinant Human Anti-WTA Antibody(HPAB-N0298-YC) in HPLC

    Human Anti-WTA Recombinant Antibody (HPAB-N0298-YC) (CAT# HPAB-N0298-YC)
    Application: FuncS

    Figure 2 Recombinant Humanized Anti-Tau Antibody (MOB-0054SW) in ELISA

    Human Anti-Tau Recombinant Antibody (MOB-0054SW) (CAT# MOB-0054SW)
    Application: ELISA, FuncS

    Figure 5 Human Anti-IAV H3N2 HA Recombinant Antibody (PABJ-0152) in Dot Blot

    Human Anti-IAV H3N2 HA Recombinant Antibody (clone S5V2-29) (CAT# PABJ-0152)
    Application: ELISA, Neut, FuncS

    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare