Anti-Human TfR Recombinant Antibody (3TF12)
CAT#: TAB-623CT
Recombinant monoclonal antibody specifically binds to TfR. This antibody can be potentially used in treating various human cancers and diseases that express transferrin receptor. It can inhibit the binding of Tf to the TfR.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to endosomes & lysosomes.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28598/546_F8_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/207_B2_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/208_B2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_3.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Pachytene spermatocytes
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_6_6.jpg
Normal Tissue
Figure 7 Bone marrow
Hematopoietic cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_6_4.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072274-TFRC
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Specifications
- Host Species
- Human
- Derivation
- Human antibody phage display library
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 3TF12
- Applications
- Used for immunoassay techniques such as: Western Blot
- Related Disease
- Bladder cancer, colon cancer, prostate cancer, and pancreatic cancer
Target
REVIEWS AND Q&AS
CITATIONS
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Customer Review
There are currently no Customer reviews or questions for TAB-623CT. Click the button above to contact us or submit your feedback about this product.
Excellent for WB
Great antibody for Western Blot analysis. We observed no nonspecific bands, and the target protein was clearly defined. Highly recommend this product.
Accurate and reliable results
We've used the Anti-Human TfR Recombinant Antibody (3TF12) extensively in our lab, and it has never failed to provide accurate and reliable results. A must-have for any TfR research.
High specificity and minimal cross-reactivity
Very pleased with the performance of the 3TF12 antibody in our in vitro assays. High specificity and minimal cross-reactivity, exactly what we needed. Now The 3TF12 antibody is now a staple in our lab for TfR-related studies.
Q&As
-
Is the Anti-Human TfR Recombinant Antibody (3TF12) validated for WB?
A: Yes, this antibody has been tested for WB on cryosections and paraffin-embedded tissues.
-
How does the 3TF12 antibody perform in Western Blot analysis?
A: The Anti-Human TfR Recombinant Antibody (3TF12) provides clear and specific bands at the expected molecular weight, confirming its effectiveness in Western Blot.
-
Are there any reported differences in performance between the Anti-Human TfR Recombinant Antibody (3TF12) and other commonly available anti-TfR antibodies?
A: The 3TF12 antibody has been reported to have higher specificity and sensitivity compared to several other commercially available anti-TfR antibodies, making it preferable for precise applications.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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Lot Number:
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