Neocarzinostatin scaffold protein anti-Chicken Lysozyme (CAT#: SNE-L146)
The Neocarzinostatin that bound lysozyme was isolated from the library using Phage display techonology. After affinity maturation, Neocarzinostatin variants were identified having affinities (KD=10 μM) for lysozyme as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm, the Golgi apparatus & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66182/1763_E3_3_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm, the Golgi apparatus & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66182/1763_E3_3_selected.jpg
Figure 2 IHC staining of human salivary gland
(High expression. RNA expression: 21115.5 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_1_val_selected.jpg
(High expression. RNA expression: 21115.5 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_1_val_selected.jpg
Figure 3 IHC staining of human skeletal muscle
(Low expression. RNA expression: 34.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_6_val_selected.jpg
(Low expression. RNA expression: 34.0 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_6_val_selected.jpg
Figure 4 Colon
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_3.jpg
(Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_9_5.jpg
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_9_5.jpg
Figure 6 Testis
(Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55/231_A_5_6.jpg
(Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55/231_A_5_6.jpg
Figure 7 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_8.jpg
Figure 8 RNA cell line category: Cell line enriched (OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090382-LYZ
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090382-LYZ
Specifications
- Scaffold Name
- Neocarzinostatin
- Origin
- Enediyne-chromoprotein family
- Core Structure
- β-sandwich
- Variable Regions
- Loop grafting; binding cleft randomization (13 aa)
- Target
- Lysozyme
- Species Reactivity
- Chicken
- Expression Host
- E. coli
- Affinity Constant
- 10 μM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- enediyne-chromoprotein family; Neocarzinostatin; LYZC
- Gene ID
- 396218
- UniProt ID
- P00698
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LYZ"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Single Domain Antibody Products
Fab Antibody Products
Humanized Antibody Products
Mouse Antibody Products
Human Antibody Products
MHC Tetramer Products for Other Applications
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3387z | Mouse Anti-LYZ Recombinant Antibody (clone 39H8) | WB, FC, ICC, IF, IHC | Mouse IgG2a |
| MOB-132YJL | Mouse Anti-LYZ Recombinant Antibody (clone muHYHEL-10) | WB, IHC, FuncS | Mouse IgG1, κ |
| MOB-111YJL | Human Anti-LYZ Recombinant Antibody (clone HYHEL-10 Y53D) | ELISA, FC, IHC | Human IgG1 |
| MOB-112YJL | Human Anti-LYZ Recombinant Antibody (clone HYHEL-10 Y53D,Y58F) | ELISA, FC, IHC | Human IgG1 |
| VS12-QX6 | Rabbit Anti-LYZ Antibody (VS12-QX6) | IA, Diagnostics, ID, Latex agglutination | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for SNE-L146. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
-1-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
