PDZ domain scaffold protein anti-Human EFNB2

CAT#: SPD-L159

The PDZ domain that bound EFNB2 was isolated from the library using phage display techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities for EFNB2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IF staining of human cell line U-251 MG Figure 3 IHC staining of human kidney Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Liver Figure 7 Kidney Figure 8 Testis Figure 9 Skin Figure 10 RNA cell line category: Cell line enhanced (AF22, OE19, SH-SY5Y)

Specifications

  • Scaffold Name
  • PDZ domain
  • Origin
  • PSD-95 protein
  • Core Structure
  • β-sheet
  • Target
  • EFNB2
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli

Target

  • Alternative Names
  • PSD-95 protein; PDZ domain; HTKL; EPLG5; Htk-L; LERK5
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