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    Recombinant Human Anti-RET Antibody (CAT#: MHH-844)

    Recombinant Human Antibody is specific to RET, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-RET mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-RET mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line MCF7
    Figure 1 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8356/1081_D1_2_selected.jpg
    Figure 2 IHC staining of human parathyroid gland
    Figure 2 IHC staining of human parathyroid gland
    (Immunohistochemical staining of human parathyroid gland shows strong positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8_selected.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_B_8_5.jpg
    Figure 4 Parathyroid gland
    Figure 4 Parathyroid gland
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (MCF7, NB-4, SH-SY5Y, THP-1)
    Figure 7 RNA cell line category: Cell line enhanced (MCF7, NB-4, SH-SY5Y, THP-1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165731-RET/subcellular

    Specifications

    • Immunogen
    • resonance energy transfer
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native resonance energy transfer
    • Applications
    • Can be useful in applications such as: Western blot; Neutralization; Functional Study

    Product Property

    • Purity
    • >95% (SDS-PAGE)
    • Storage
    • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

    Target

    • Alternative Names
    • resonance energy transfer; RET; Förster resonance energy transfer; FRET; fluorescence resonance energy transfer; FRET; resonance energy transfer; RET; electronic energy transfer; EET

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    MOB-844-F(E) Recombinant Anti-RET Antibody Fab Fragment RIA, WB, FuncS Fab
    MHH-844-F(E) Recombinant Human Anti-RET Antibody Fab Fragment ELISA, WB, FC, FuncS Fab

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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