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    Anti-Human RET Recombinant Antibody (Y078) (CAT#: TAB-066MZ)

    The fully human anti-RET antibody may be conjugated to the DM1 and DM4 derivatives of the potent cytotoxic agent maytansine using thioether and disulfide linkers, respectively, which demonstrated antitumor activity in preclinical models.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line MCF7
    Figure 1 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8356/1081_D1_2_selected.jpg
    Figure 2 IHC staining of human parathyroid gland
    Figure 2 IHC staining of human parathyroid gland
    (Immunohistochemical staining of human parathyroid gland shows strong positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8_selected.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_B_8_5.jpg
    Figure 4 Parathyroid gland
    Figure 4 Parathyroid gland
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_3_8.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2581/6496_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (MCF7, NB-4, SH-SY5Y, THP-1)
    Figure 7 RNA cell line category: Cell line enhanced (MCF7, NB-4, SH-SY5Y, THP-1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165731-RET/subcellular

    Specifications

    • Host Species
    • Human
    • Type
    • Human antibody
    • Specificity
    • Human
    • Clone
    • Y078
    • Applications
    • Cyt, IHC, FC
    • Related Disease
    • Breast cancer

    Applications

    • Application Notes
    • The RET antibody has been reported in applications of Cytotoxicity, Immunohistochemistry, Flow Cytometry.

    Target

    • Alternative Names
    • PTC; MTC1; HSCR1; MEN2A; MEN2B; RET51; CDHF12; CDHR16; RET-ELE1

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone Y078"

    See other products for "RET"

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    CAT Product Name Application Type
    MOB-844 Recombinant Anti-RET Antibody ELISA, IP, FuncS IgG
    MHH-844 Recombinant Human Anti-RET Antibody WB, Neut, FuncS IgG
    MOB-1794CT Recombinant Mouse anti-Human RET Monoclonal antibody (NN0630-20G23) WB
    ZG-065R Mouse Anti-RET Recombinant Antibody (ZG-065R) WB, ELISA Mouse IgG
    VS3-CJ479 Rabbit Anti-RET Recombinant Antibody (VS3-CJ479) WB, ICC, IF, IHC, IP, FC Rabbit IgG

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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