Z-domain of protein A scaffold protein anti-Human Transferrin

Name: Z-domain of protein A scaffold protein anti-Human Transferrin
SKU: SZA-L242
Rating: 5 (1 reviews)

CAT#: SZA-L242

This transferrin specific binding protein (Z-domain of protein A) was investigated by an α-helix shuffling strategy. The primary scaffold protein was from a naive combinatorial library of the three-helix bundle Z domain derived from staphylococcal protein A. A hierarchical library was constructed through selective re-randomization of six amino acid positions in one of the two α-helices of the domain, making up the Taq DNA polymerase binding surface. After selections using monovalent phage display technology, second generation variants were identified having affinities (KD=400 nM) for transferrin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Gene Expression

Normal Tissue Figure 1 Liver

Hepatocytes
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_4.jpg

Normal Tissue Figure 2 Kidney

Cells in tubules
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5692/159943_A_8_5.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enriched (Hep G2)

Cell lines ordered by descending RNA expression order.

RNA Expression Figure 3 RNA cell line category: Cell line enriched (Hep G2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091513-TF

❮

❯

Specifications

Scaffold Name
Z-domain of protein A

Origin
Staphylococcal protein A

Core Structure
3-α helixes

Variable Regions
13 Residues on first and second helix surface

Target
Transferrin

Species Reactivity
Human

Expression Host
BL21 (DE3) cells

Affinity Constant
400 nM

Applications
ELISA; IHC; Microscopy; FC; WB; FuncS

Target

Alternative Names
Staphylococcal protein A; Z-domain of protein A; TFQTL1; PRO1557; PRO2086; HEL-S-71p

Gene ID
7018

UniProt ID
P02787

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for SZA-L242. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

AGE-RAGE Signaling Pathway in Diabetic Complications

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - SZA-L242.pdf

MSDS

MSDS - SZA-L242.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "TF"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
PABL-343	Mouse Anti-TF Recombinant Antibody (clone 6A6)	WB, ELISA, IF, FuncS	Mouse IgG
PABW-164	Recombinant Mouse Anti-TF(Galβ1-3GalNAcα) Antibody (JAA-F11)	FuncS, IHC, FC, Cyt	IgG
HPAB-2578LY	Human Anti-TF Recombinant Antibody (HPAB-2578LY)	ELISA	Humanized IgG
HPAB-0717YY	Human Anti-TF Recombinant Antibody (HPAB-0717YY)	ELISA, Inhib, WB, FuncS	Humanized IgG1
HPAB-0718YY	Human Anti-TF Recombinant Antibody (HPAB-0718YY)	ELISA, Inhib, WB, FuncS	Humanized IgG1

CAT	Product Name	Application	Type
PFBL-343	Mouse Anti-TF Recombinant Antibody (clone 6A6); Fab Fragment	WB, ELISA, IF, FuncS	Mouse Fab
PFBW-121	Mouse Anti-TF Recombinant Antibody (clone 5G9); Fab Fragment	WB, IHC, IF, FuncS	Mouse Fab
PFBC-122	Human Anti-TF Recombinant Antibody (clone hATR-5); Fab Fragment	Block	Humanized Fab
HPAB-0717YY-F(E)	Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0717YY-F(E))	ELISA, Inhib, WB, FuncS	Humanized Fab
HPAB-0718YY-F(E)	Human Anti-TF Recombinant Antibody; Fab Fragment (HPAB-0718YY-F(E))	ELISA, Inhib, WB, FuncS	Humanized Fab

CAT	Product Name	Application	Type
TAB-0510CL	Mouse Anti-TF Recombinant Antibody (TAB-0510CL)	WB, IF, ELISA	Mouse IgG
TAB-0510CL-S(P)	Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-0510CL-S(P))	WB, IF, ELISA	Mouse scFv
TAB-598CT	Mouse Anti-TF Recombinant Antibody (TAB-598CT)	ELISA, FC	Mouse IgG1. κ
TAB-598CT-S(P)	Mouse Anti-TF Recombinant Antibody; scFv Fragment (TAB-598CT-S(P))	ELISA, FC	Mouse scFv
TAB-598CT-F(E)	Mouse Anti-TF Recombinant Antibody; Fab Fragment (TAB-598CT-F(E))	ELISA, FC	Mouse Fab

CAT	Product Name	Application	Type
TAB-599CT	Anti-Human TF Recombinant Antibody (ATR-5)	ELISA, FC	Humanized antibody
TAB-600CT	Anti-Human TF Recombinant Antibody (ATR-2)	ELISA, FC	Humanized antibody
TAB-599CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (ATR-5)	ELISA, FC	Humanized antibody
TAB-600CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (ATR-2)	ELISA, FC	Humanized antibody
TAB-601CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (ATR-8)	ELISA, FC, BL	Humanized antibody

CAT	Product Name	Application	Type
TAB-602CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (3e10)	ELISA, BL	Human antibody
TAB-603CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (3h2)	ELISA, BL	Human antibody
TAB-604CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (2c1)	ELISA, BL	Human antibody
TAB-605CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (2c11)	ELISA, BL	Human antibody
TAB-606CT-S(P)	Anti-Human TF Recombinant Antibody scFv Fragment (2d3)	ELISA, BL	Human antibody

CAT	Product Name	Application	Type
Gly-175LC	Recombinant Anti-Human TF Antibody (Non-glycosylated)	ELISA	Mouse antibody

CAT	Product Name	Application	Type
BRD-0860MZ	Chicken Anti-Transferrin Polyclonal IgY	ELISA	Chicken antibody

CAT	Product Name	Application
MHC-LC1106	PE-H2-Aa/Gallus gallus TF (GNSHRGAIEWEGIESG) MHC Tetramer	FCM
MHC-LC1107	APC-H2-Aa/Gallus gallus TF (GNSHRGAIEWEGIESG) MHC Tetramer	FCM
MHC-LC1108	BV421-H2-Aa/Gallus gallus TF (GNSHRGAIEWEGIESG) MHC Tetramer	FCM

CAT	Product Name	Application	Type
NEUT-1996CQ	Mouse Anti-TF Recombinant Antibody (clone HTF-14)	WB, Neut, ELISA, ICC, IF, IHC, IHC-P, RIA	Mouse IgG1

CAT	Product Name	Application	Type
NEUT-2022CQ	Mouse Anti-TF Recombinant Antibody (clone A68-B/A11)	ELISA, Inhib, IHC-P, IHC-Fr	Mouse IgM

CAT	Product Name	Application	Type
MOR-3535	Rabbit Anti-TF Recombinant Antibody (clone DS3535AB)	IHC-P, IP, WB	Rabbit IgG

CAT	Product Name	Application	Type
FAMAB-0318CQ-S(P)	Mouse Anti-TF Recombinant Antibody (clone PTF.02); scFv Fragment	ELISA, FC	Mouse scFv
FAMAB-0319CQ-S(P)	Mouse Anti-TF Recombinant Antibody (clone TW4.20); scFv Fragment	ELISA, WB, FC, Inhib	Mouse scFv
HPAB-0717YY-S(P)	Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0717YY-S(P))	ELISA, Inhib, WB, FuncS	Human scFv
HPAB-0718YY-S(P)	Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0718YY-S(P))	ELISA, Inhib, WB, FuncS	Human scFv
HPAB-0719YY-S(P)	Human Anti-TF Recombinant Antibody; scFv Fragment (HPAB-0719YY-S(P))	ELISA, Inhib, WB, FuncS	Human scFv

CAT	Product Name	Application	Type
VS-0325-XY2269	Anti-TF Immunohistochemistry Kit	IHC
VS-0525-XY7178	Anti-Human TF Immunohistochemistry Kit	IHC

Specific Inquiry

Add to compare

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Anti-Human TNF Antibody (TAB-010) in ELISA

Anti-Human TNF Recombinant Antibody (TAB-010) (CAT# TAB-010)
Application: WB, FC, IP, ELISA, Neut, FuncS, IF

Figure 2 Anti-Human CXCR4 Recombinant Antibody (TAB-H72) in HPLC

Human Anti-Human CXCR4 Recombinant Antibody (TAB-H72) (CAT# TAB-H72)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 2 Anti-Human Met (TAB-190-F(E)) in ELISA

Anti-Human Met(Onartuzumab) (CAT# TAB-190-F(E))
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 5 Anti-Human folate receptor 1 Antibody (TAB-113) in SEC-HPLC

Anti-Human folate receptor 1 Recombinant Antibody (TAB-113) (CAT# TAB-113)
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC

Figure 10 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-770) resulted in an increase of IFN-γ production.

Anti-PDCD1 Recombinant Antibody (TAB-770) (CAT# TAB-770)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 3 Anti-Human FLT3 Therapeutic Antibody (TAB-291CL) in ELISA

Anti-Human FLT3 Recombinant Antibody (IMC-EB10) (CAT# TAB-291CL)
Application: WB, IHC, FC, Cyt, ELISA

Figure 2 Anti-Human IL21R Recombinant Antibody (TAB- 416CL) in DB

Anti-Human IL21R Recombinant Antibody (PF-05230900) (CAT# TAB-416CL)
Application:

Figure 3 Anti-Human VEGF Antibody Fab Fragment (TP-104CL) in DB

Human Anti-Human VEGF Recombinant Antibody; Fab Fragment (TP-104CL) (CAT# TP-104CL)
Application:

Figure 9 Anti-IAV HA Recombinant Antibody (PABL-213) in DB

Recombinant Human Anti-IAV HA Antibody (CT149) (CAT# PABL-213)
Application: WB, Neut, FuncS

Figure 2 Anti-Human EGFR Antibody (PABW-088) in DB

Mouse Anti-EGFR Recombinant Antibody (clone 7A7) (CAT# PABW-088)
Application: ELISA, WB

Figure 2 Anti-Human RAGE Recombinant Antibody (TAB-293CT) in ELISA

Anti-Human RAGE Recombinant Antibody (XT-M4) (CAT# TAB-293CT)
Application: WB, ELISA, Neut, PK

Figure 2 Anti-Human RNF43 Recombinant Antibody scFv Fragment (TAB-328CT-S(P)) in HPLC

Humanized Anti-RNF43 Recombinant Antibody; scFv Fragment (TAB-328CT-S(P)) (CAT# TAB-328CT-S(P))
Application: WB, ELISA, FC, IHC, IP

Figure 2 Anti-Human TREM1 Recombinant Antibody (TAB-167CQ) in SDS-PAGE

Human Anti-TREM1 Recombinant Antibody (TAB-167CQ) (CAT# TAB-167CQ)
Application: ELISA, FC, WB, Block

Figure 3 Anti-GPC3 Antibody (TAB-263CQ) in Dot Blot

Anti-Human GPC3 Recombinant Antibody (TAB-263CQ) (CAT# TAB-263CQ)
Application: ELISA, Inhib, IHC

Figure 2 Anti-alpha 4 beta 7 Antibody (TAB-718LC) in Dot Blot

Anti-human Integrin α4β7 Recombinant Antibody (J19) (TAB-718LC) (CAT# TAB-718LC)
Application: ELISA, FC

Figure 5 Anti-Human INHBB Recombinant Antibody (TAB-0652CLV) in Dot Blot

Mouse Anti-INHBB Recombinant Antibody (TAB-0652CLV) (CAT# TAB-0652CLV)
Application: WB, IHC, ELISA, FC

Figure 5 Mouse Anti-HIV-1 p24 Recombinant Antibody (clone AG3.0) (MRO-961CQ) in SEC-HPLC.

Mouse Anti-HIV-1 p24 Recombinant Antibody (clone AG3.0) (CAT# MRO-961CQ)
Application: ELISA

Figure 2 Human Anti-NOTCH4 Recombinant Antibody (HPAB-0068-CN) in HPLC

Human Anti-NOTCH4 Recombinant Antibody (HPAB-0068-CN) (CAT# HPAB-0068-CN)
Application: Neut, IF

Figure 1 Human IgG2, kappa Isotype Control Antibody (MOB-197CQ) in SDS-PAGE

Human IgG2, kappa Isotype Control Antibody (CAT# MOB-197CQ)
Application: FC, ELISA

Figure 3 Mouse Anti-Human MSLN Antibody (HPAB-0886-FY) in WB

Mouse Anti-MSLN Recombinant Antibody (HPAB-0886-FY) (CAT# HPAB-0886-FY)
Application: FC

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.