A*02:01/Human BMI1 (TLQDIVYKL) MHC Tetramer
CAT#: MHC-CN0452
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear bodies.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30471/1564_A5_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30472/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human adrenal gland
Immunohistochemical staining of human adrenal gland shows strong nuclear positivity in cortical cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/ihc_selected.jpg
Normal Tissue
Figure 4 Testis
Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_A_8_8.jpg
Normal Tissue
Figure 6 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_B_8_5.jpg
Normal Tissue
Figure 7 Nasopharynx
Respiratory epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_B_8_2.jpg
Normal Tissue
Figure 8 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_A_7_3.jpg
Normal Tissue
Figure 9 Kidney
Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11120/34651_A_7_5.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, U-937)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168283-BMI1
❮
❯
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- BMI1
- Antigen Species
- Human
- Peptide
- TLQDIVYKL
- Conjugate
- Unconjugated
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
- Alternative Names
- BMI1 Proto-Oncogene, Polycomb Ring Finger; Polycomb Group RING Finger Protein 4; PCGF4; RNF51; B Lymphoma Mo-MLV Insertion Region 1 Homolog (Mouse); Murine Leukemia Viral (Bmi-1) Oncogene Homolog; B Lymphoma Mo-MLV Insertion Region 1 Homolog; BMI1 Polycomb Ring Finger Proto-Oncogene; BMI1 Polycomb Ring Finger Oncogene;
- Gene ID
- 648
- UniProt ID
- P35226
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Datasheet
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COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "BMI1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0365 | Hi-Affi™ Rabbit Anti-BMI1 Recombinant Antibody (clone DS365AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0184-CN | Mouse Anti-BMI1 Recombinant Antibody (clone A11-C11) | WB, IHC, IF | Mouse IgG2a |
| MRO-0185-CN | Rabbit Anti-BMI1 Recombinant Antibody (clone CBACN-072) | WB, IF, IHC | Rabbit IgG |
| MRO-0186-CN | Mouse Anti-BMI1 Recombinant Antibody (clone B3-G5) | WB, IF, IHC, FC | Mouse IgG2a |
| VS3-CJ22 | Mouse Anti-BMI1 Recombinant Antibody (VS3-CJ22) | WB, ELISA | Mouse IgG |
| VS7-HM239 | Mouse Anti-BMI1 Recombinant Antibody (clone CBL079HM) | WB, IHC-p, IF, ICC, FCM, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0449 | PE-A*02:01/Human BMI1 (TLQDIVYKL) MHC Tetramer | FCM, IHC | |
| MHC-CN0450 | APC-A*02:01/Human BMI1 (TLQDIVYKL) MHC Tetramer | FCM, IHC | |
| MHC-CN0451 | FITC-A*02:01/Human BMI1 (TLQDIVYKL) MHC Tetramer | FCM, IHC | |
| MHC-CN0453 | PE-A*02:01/Human BMI1 (CLPSPSTPV) MHC Tetramer | FCM, IHC | |
| MHC-CN0454 | APC-A*02:01/Human BMI1 (CLPSPSTPV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY31 | AbPlus™ Anti-BMI1 Magnetic Beads (229F6) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC21 | Rabbit Anti-BMI1 Antibody (VS-0924-YC21) - Cancer Stem Cell Marker | IF | Rabbit IgG |
| VS-0924-YC22 | Rabbit Anti-BMI1 Antibody (VS-0924-YC22) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY249 | Anti-BMI1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY792 | Anti-Mouse BMI1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY791 | Anti-Human BMI1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC101 | CytoStream™ Mouse Anti-BMI1 Recombinant Antibody (VS13-YC101) | WB, ICC, IF, IHC-P, FC | Mouse IgG2a |
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