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    Human Anti-ABCB1 Recombinant Antibody (PABC-444) (CAT#: PABC-444)

    This product is a recombinant human antibody that can recognize ABCB1. This antibody is a human ABCB1-specific inhibitory antibody. This antibody recognizes a conformational epitope of ABCB1 that involves residues from TM1 and TM2 and the extracellular loops EL1, EL3, and EL4.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2199/if_selected.jpg
    Figure 2 IF staining of human cell line U-2 OS
    Figure 2 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/74614/1893_J14_31_selected.jpg
    Figure 3 IF staining of human cell line U-251 MG
    Figure 3 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/203_B4_1_blue_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_B_9_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_A_9_4.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
    Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000085563-ABCB1

    Specifications

    • Host Species
    • Human
    • Derivation
    • Chimeric (mouse/human)
    • Type
    • Human IgG1, κ
    • Specificity
    • Human ABCB1
    • Species Reactivity
    • Human
    • Applications
    • FuncS, FC, Block, IP, IHC

    Product Property

    • Purity
    • >95% as determined by analysis by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been reported for use in Functional Assay, Flow Cytometry, Blocking, Immunoprecipitation and Immunohistochemistry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

    Target

    • Alternative Names
    • ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ABCB1"

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    CAT Product Name Application Type
    MOB-22 Recombinant Anti-human ABCB1 Antibody WB, ELISA, IHC, FuncS IgG
    MHH-22 Recombinant Human Anti-human ABCB1 Antibody FC, Neut, Funcs IgG
    HPAB-M0001-YC Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6) IHC Mouse IgG
    HPAB-0076-YJ Mouse Anti-ABCB1 Recombinant Antibody (HPAB-0076-YJ) IF, FC, IHC-P, ELISA Mouse IgG2a, κ
    VS3-QX2 Mouse Anti-ABCB1 Recombinant Antibody (clone 1G6) WB, IP, IF Mouse IgG1

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