Human Anti-ABCB1 Recombinant Antibody Fab Fragment (PFBC-444) (CAT#: PFBC-444)
This product is a recombinant human antibody Fab fragment that can recognize ABCB1. This antibody is a human ABCB1-specific inhibitory antibody. This antibody recognizes a conformational epitope of ABCB1 that involves residues from TM1 and TM2 and the extracellular loops EL1, EL3, and EL4.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2199/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2199/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74614/1893_J14_31_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74614/1893_J14_31_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/203_B4_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/203_B4_1_blue_red_green.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_B_9_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_B_9_5.jpg
Figure 5 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_A_9_4.jpg
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_A_9_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000085563-ABCB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000085563-ABCB1
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Human Fab
- Specificity
- Human ABCB1
- Species Reactivity
- Human
- Applications
- FC, Block, IP, IHC
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
Fab Antibody Products
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-22 | Recombinant Anti-human ABCB1 Antibody | WB, ELISA, IHC, FuncS | IgG |
| PABC-444 | Human Anti-ABCB1 Recombinant Antibody (PABC-444) | FuncS, FC, Block, IP, IHC | Human IgG1, κ |
| HPAB-M0001-YC | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6) | IHC | Mouse IgG |
| HPAB-0076-YJ | Mouse Anti-ABCB1 Recombinant Antibody (HPAB-0076-YJ) | IF, FC, IHC-P, ELISA | Mouse IgG2a, κ |
| FAMAB-1015CQ | Mouse Anti-ABCB1 Recombinant Antibody (clone MRK16) | FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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