Mouse Anti-ALK Recombinant Antibody (VS-0224-XY7) (CAT#: VS-0224-XY7)
The product is a mouse monoclonal antibody, which specifically recognizes ECD region of human ALK (ALK receptor tyrosine kinase). It can be used for Enzyme-linked immunosorbent assay, Immunofluorescence and Immunocytochemistry.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/1416_A5_3_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/1416_A5_3_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26100_B_8_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26100_B_8_5.jpg
Figure 3 Cerebellum
(Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26100_B_7_8.jpg
(Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26100_B_7_8.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26075_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26075_A_7_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26075_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10694/26075_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enriched (SH-SY5Y)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171094-ALK
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171094-ALK
Specifications
- Immunogen
- Mouse myeloma cell line NS0-derived recombinant human ALK/CD246 (AA 19-1038)
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human ALK
- Species Reactivity
- Human
- Applications
- ELISA, Immunofluorescence, Immunocytochemistry
- Related Disease
- Neuroblastoma
Product Property
- Purification
- Protein A purified
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested in Immunofluorescence and Immunocytochemistry at a concentration of 8-25 ug/mL.
Target
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ALK"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0296MZ | Mouse Anti-ALK Recombinant Antibody (clone BLK2) | IHC | Mouse IgG3 |
| HPAB-0138-YC | Mouse Anti-ALK Recombinant Antibody (HPAB-0138-YC) | ELISA, FC, WB, Inhib | Mouse IgG |
| HPAB-0139-YC | Mouse Anti-ALK Recombinant Antibody (HPAB-0139-YC) | ELISA, WB, FC, Agonist | Mouse IgG |
| HPAB-0140-YC | Mouse Anti-ALK Recombinant Antibody (HPAB-0140-YC) | ELISA, FC, WB | Mouse IgG |
| HPAB-0141-YC | Mouse Anti-ALK Recombinant Antibody (HPAB-0141-YC) | ELISA, FC, RIA, Inhib | Mouse IgG, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0147 | Hi-Affi™ Rabbit Anti-ALK Recombinant Antibody (clone DS147AB) | IHC-P | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0138-YC-S(P) | Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0138-YC-S(P)) | ELISA, FC, WB | Mouse scFv |
| HPAB-0139-YC-S(P) | Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0139-YC-S(P)) | ELISA, FC, WB | Mouse scFv |
| HPAB-0140-YC-S(P) | Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0140-YC-S(P)) | ELISA, FC, WB | Mouse scFv |
| HPAB-0141-YC-S(P) | Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0141-YC-S(P)) | ELISA, FC, RIA | Mouse scFv |
| HPAB-0143-YC-S(P) | Mouse Anti-ALK Recombinant Antibody (clone D10); scFv Fragment | ELISA, FC, Stim | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0138-YC-F(E) | Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0138-YC-F(E)) | ELISA, FC, WB | Mouse Fab |
| HPAB-0139-YC-F(E) | Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0139-YC-F(E)) | ELISA, FC, WB | Mouse Fab |
| HPAB-0140-YC-F(E) | Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0140-YC-F(E)) | ELISA, FC, WB | Mouse Fab |
| HPAB-0141-YC-F(E) | Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0141-YC-F(E)) | ELISA, FC, RIA | Mouse Fab |
| HPAB-0143-YC-F(E) | Mouse Anti-ALK Recombinant Antibody (clone D10); Fab Fragment | ELISA, FC, Stim | Mouse Fab |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-004CN | Human Anti-ALK Recombinant Antibody (clone ESBA521) | ELISA, WB, FuncS | Human IgG |
| NS-004CN-F(E) | Human Anti-ALK Recombinant Antibody (clone ESBA521); Fab Fragment | ELISA, WB | Human Fab |
| NS-004CN-S(P) | Human Anti-ALK Recombinant Antibody (clone ESBA521); scFv Fragment | ELISA, WB | Human scFv |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF574 | A*02:01/Human Mutant anaplastic lymphoma kinase (SLAMLDLLHV) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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