Mouse Anti-APOE Recombinant Antibody (clone 2E8); Fab Fragment (CAT#: HPAB-0115CQ-F(E))
This product is a recombinant mouse antibody Fab fragment that recognizes APOE. 2E8, the monoclonal antibody specific for the low-density lipoprotein (LDL) receptor-binding region of apolipoprotein E (apoE). 2E8, is known to the interaction of apoE with the LDL receptor by binding to epitopes within the receptor-binding region of apoE
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/1270_D3_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/1270_D3_2_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_B_9_5.jpg
Figure 3 High expression in liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_7_4.jpg
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, CACO-2, Hep G2, HSkMC, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130203-APOE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130203-APOE
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human APOE
- Species Reactivity
- Human
- Clone
- 2E8
- Applications
- ELISA, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Apolipoprotein E; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; ApoE4; LPG; AD2;
- Gene ID
- 348
- UniProt ID
- P02649
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1659z | Mouse Anti-APOE Recombinant Antibody (clone 41D9) | WB, ELISA, FC, ICC, IF, IHC, IP | Mouse IgG1, κ |
| MRO-0113-CN | Rabbit Anti-APOE Recombinant Antibody (clone CBACN-038) | WB, IF, IHC, IP | Rabbit IgG |
| MRO-1656-CN | Rabbit Anti-APOE Polyclonal Antibody (MRO-1656-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-XY85 | Mouse Anti-APOE Recombinant Antibody (clone 1H4) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS7-HM120 | Mouse Anti-APOE Recombinant Antibody (clone CBL044HM) | WB, IHC-p, IF, FCM, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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