AibGenesis™ Rabbit Anti-CCR3 Recombinant Antibody (AibG-Rb-CC297)
CAT#: VS-0426-FY297
Developed via our AI-powered antibody discovery platform, this Rabbit IgG targets CCR3. Validated for IHC in Human, Mouse, and Rat, it serves as a highly specific marker for eosinophil recruitment in allergy, asthma research, and Th2-mediated inflammatory responses.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69514/1943_C10_3_selected.jpg
Normal Tissue
Figure 2 Esophagus
Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_B_6_1.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3795/10573_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (RPMI-8226)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000183625-CCR3
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CCR3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-CC297
- Applications
- Immunohistochemistry
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Eosinophilic Asthma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 150 mM NaCl, 50% Glycerol
- Preservative
- 0.02% New type preservative N
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry (1:50-1:200)
Target
- Alternative Names
- CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3
- Gene ID
- 1232
- UniProt ID
- P51677
- Long Name
- C-C Motif Chemokine Receptor 3
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P51677)
Modification sites at neXtProt (NX_P51677)
Glycosylation from GlyGen (P51677) 2 sites, 1 O-linked glycan (2 sites)
- Protein Refseq
- XP_006713023.1; XP_016861174.1; XP_054201143.1; XP_054201144.1; NP_001158152.1
- Function
- Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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