Human Anti-CCR4 Recombinant Antibody (clone 9E) (CAT#: HPAB-1005WJ)
This product is a human antibody binds to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1. Different concentrations of 17G, 9E and KM3060var antibodies were tested in flow cytometry for binding to avian DT40 cells stably transfected with human CCR4.
Hagemann, U. B., Gunnarsson, L., Geraudie, S., Scheffler, U., Griep, R. A., Reiersen, H., ... & Kiprijanov, S. M. (2014). Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis. PLoS One, 9(7).
Specifications
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- Human CCR4
- Species Reactivity
- Human
- Clone
- 9E
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The 9E antibody has been reported in applications of FC.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- C-C Motif Chemokine Receptor 4; Chemokine (C-C Motif) Receptor 4; C-C CKR-4; CC-CKR-4; CMKBR4; CCR-4; K5-5; C-C Chemokine Receptor Type 4;
- Gene ID
- 1233
- UniProt ID
- P51679
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187 | Human Anti-CCR4 Recombinant Antibody (TAB-187) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG1, κ |
| TAB-1530CL | Human Anti-CCR4 Recombinant Antibody (TAB-1530CL) | Depletion, FuncS | Human IgG4 |
| TAB-1530CL-S(P) | Human Anti-CCR4 Recombinant Antibody; scFv Fragment (TAB-1530CL-S(P)) | Depletion, FuncS | Human scFv |
| TAB-1530CL-F(E) | Human Anti-CCR4 Recombinant Antibody; Fab Fragment (TAB-1530CL-F(E)) | Depletion, FuncS | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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