AbPlus™ Anti-CD27 Magnetic Beads (2F2)
CAT#: VS-0424-XY51
The AbPlus Anti-CD27 Magnetic Beads (2F2) is an innovative affinity resin which is bound with anti-CD27 specific antibody (2F2). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CD27 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2420/6097_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2420/6097_A_5_8.jpg
Normal Tissue
Figure 3 High expression in lymph node.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_7_8_val_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_8_8.jpg
Normal Tissue
Figure 5 Tonsil
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_5_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139193-CD27
RNA Expression
Figure 3 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139193-CD27
❮
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-CD27 specific antibody (2F2)
- Target
- CD27
- Target Species
- Human
- Antibody Clone
- 2F2
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
- Alternative Names
- CD27; CD27 molecule; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7
- Gene ID
- 939
- UniProt ID
- P26842
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022LC | Human Anti-CD27 Recombinant Antibody (TAB-022LC) | ELISA | Humanized antibody |
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| TAB-023LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-023LC-S(P)) | ELISA | Humanized scFv |
| TAB-024LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-024LC-S(P)) | ELISA | Humanized scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0299-CN-F(E) | Human Anti-CD27 Recombinant Antibody; Fab Fragment (HPAB-0299-CN-F(E)) | ELISA, FC, Block | Human Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H74 | Afuco™ Anti-CD27 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H74) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-229CQ | Hamster Anti-CD27 Recombinant Antibody (clone LG.3A10) | FC, FuncS, IHC-Fr | Armenian hamster IgG |
| FN-261CQ | Mouse Anti-CD27 Recombinant Antibody (clone O323) | FC | Mouse IgG1 |
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|---|---|---|---|
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