Recombinant Anti-CD27 Vesicular Antibody, EV Displayed (VS-0425-YC688)
CAT#: VS-0425-YC688
The Recombinant Anti-CD27 Vesicular Antibody, EV Displayed (VS-0425-YC688) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD27-expressed cells or tissues. CD27, a transmembrane receptor, is involved in signaling pathways related to apoptosis and JNK cascade regulation, with its human ortholog implicated in specific syndromes.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2420/6097_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2420/6097_A_5_8.jpg
Normal Tissue
Figure 3 High expression in lymph node.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_7_8_val_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_8_8.jpg
Normal Tissue
Figure 5 Tonsil
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2420/6097_A_5_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000139193-CD27
RNA Expression
Figure 3 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139193-CD27
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD27
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD27 molecule
- Biological Process
- Apoptosis
- Molecular Function
- Receptor
- Cellular Localization
- Vesicles
- Introduction
- Enables transmembrane signaling receptor activity. Involved in CD27 signaling pathway; negative regulation of apoptotic process; and positive regulation of JNK cascade. Acts upstream of or within negative regulation of T cell apoptotic process. Located in external side of plasma membrane. Is active in plasma membrane. Is expressed in several structures, including femur; hemolymphoid system; intestine; pituitary gland; and reproductive system. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2. Orthologous to human CD27 (CD27 molecule).
- Alternative Names
- S152, Tnfrsf7, Tp55
- Gene ID
- 21940
- UniProt ID
- P41272
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2370z | Mouse Anti-CD27 Recombinant Antibody (clone 16G8) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MRO-0291-CN | Rabbit Anti-CD27 Recombinant Antibody (clone JB40-98) | WB, IF, IHC, FC | Rabbit IgG |
| FN-229CQ | Hamster Anti-CD27 Recombinant Antibody (clone LG.3A10) | FC, FuncS, IHC-Fr | Armenian hamster IgG |
| ZG-0027U | Rabbit Anti-CD27 Recombinant Antibody (clone 4A1) | ELISA, WB | Rabbit IgG |
| VS-0723-WK285 | Rabbit Anti-CD27 Recombinant Antibody (VS-0723-WK285) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H74 | Human Anti-Human CD27 Recombinant Antibody (TAB-H74) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-013LC | Rat Anti-CD27 Recombinant Antibody (TAB-013LC) | ELISA, CDC, ADCC | Rat IgG2a |
| TAB-014LC | Rat Anti-CD27 Recombinant Antibody (TAB-014LC) | ELISA, FC, CDC, ADCC | Rat IgG1 |
| TAB-015LC | Rat Anti-CD27 Recombinant Antibody (TAB-015LC) | ELISA, FC, CDC, ADCC, SPR | Rat IgG2a |
| TAB-016LC | Rat Anti-CD27 Recombinant Antibody (TAB-016LC) | ELISA, SPR | Rat IgG2b |
| TAB-017LC | Rat Anti-CD27 Recombinant Antibody (TAB-017LC) | ELISA, FC, CDC, ADCC, SPR | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022LC | Human Anti-CD27 Recombinant Antibody (TAB-022LC) | ELISA | Humanized antibody |
| TAB-022LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-022LC-S(P)) | ELISA | Humanized scFv |
| TAB-023LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-023LC-S(P)) | ELISA | Humanized scFv |
| TAB-024LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-024LC-S(P)) | ELISA | Humanized scFv |
| TAB-025LC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-025LC-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018LC-S(P) | Rat Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-018LC-S(P)) | ELISA | Rat scFv |
| TAB-019LC-S(P) | Rat Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-019LC-S(P)) | ELISA | Rat scFv |
| TAB-020LC-S(P) | Rat Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-020LC-S(P)) | ELISA | Rat scFv |
| TAB-021LC-S(P) | Rat Anti-CD27 Recombinant Antibody; scFv Fragment (TAB-021LC-S(P)) | ELISA | Rat scFv |
| TAB-032LC-S(P) | Anti-Human CD27 Recombinant Antibody scFv Fragment (F14) | SPR, FC | Chimeric antibody (rabbit/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-320CQ | Hamster Anti-CD27 Recombinant Antibody (clone LG.7F9) | FC, FuncS, Neut | Hamster IgG |
| NEUT-321CQ | Mouse Anti-CD27 Recombinant Antibody (NEUT-321CQ) | WB, Neut, FC | Mouse IgG1 |
| NEUT-322CQ | Mouse Anti-CD27 Recombinant Antibody (clone CBL803) | WB, FC, CyTOF, Neut | Mouse IgG1 |
| NEUT-323CQ | Mouse Anti-CD27 Recombinant Antibody (clone CBL185) | FC, Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0547 | Hi-Affi™ Rabbit Anti-CD27 Recombinant Antibody (clone DS547AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-096LC | Human Anti-CD27 Recombinant Antibody (MOB-096LC) | ELISA, FuncS, WB | Human IgG1, κ |
| VS-0724-XY8 | Human Anti-CD27 Agonistic Antibody (VS-0724-XY8) | ELISA, Agonistic assays | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0299-CN-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (HPAB-0299-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0300-CN-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (HPAB-0300-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-N0032-YC-S(P) | Human Anti-CD27 Recombinant Antibody; scFv Fragment (HPAB-N0032-YC-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0299-CN-F(E) | Human Anti-CD27 Recombinant Antibody; Fab Fragment (HPAB-0299-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0300-CN-F(E) | Human Anti-CD27 Recombinant Antibody; Fab Fragment (HPAB-0300-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-N0032-YC-F(E) | Human Anti-CD27 Recombinant Antibody; Fab Fragment (HPAB-N0032-YC-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H74 | Afuco™ Anti-CD27 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H74) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY51 | AbPlus™ Anti-CD27 Magnetic Beads (2F2) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC108 | Rat Anti-CD27 Recombinant Antibody Hexamer (VS-0924-YC108), CDC Enhanced | ELISA, FC, CDC, ADCC | Antibody hexamer |
| VS-0924-YC109 | Human Anti-CD27 Recombinant Antibody Hexamer (VS-0924-YC109), CDC Enhanced | ELISA, CDC, SPR | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY30 | CytoStream™ Mouse Anti-CD27 Recombinant Antibody (VS-0225-XY30) | FC, IHC | Mouse IgG1, kappa |
| VS-0225-XY31 | CytoStream™ Mouse Anti-CD27 Recombinant Antibody (VS-0225-XY31) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY16 | Mouse Anti-CD27 scFv-Fc Chimera (VS-0425-FY16) | Inhib, ELISA, FC | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1151 | Anti-Rat CD27 Immunohistochemistry Kit | IHC |
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