Mouse Anti-CD47 Recombinant Antibody (clone MABL-2) (CAT#: HPAB-1279WJ)
This product is a mouse antibody targeting human IAP. This antibody can be used as a preventive and/or remedy for various diseases such as cancer, inflammation, hormone disorders and blood diseases.
Specific Inquiry
ELISA
Figure 1 A graph shows the antibodies combining humanized H chain versions 1.1, 1.2 and 1.3 with a chimeric L chain have human IAP-binding activities comparable to that of the chimeric antibody.
ELISA
Figure 2 A graph shows the versions 1.2 and 1.3 among the antibodies combining humanized H chain versions 1.1, 1.2 and 1.3 with a chimeric L chain have binding inhibitory activities by MABL-2 nearly comparable to that of the chimeric antibody.
Cyt
Figure 3 A graph shows the humanized MABL-1 antibody and the humanized MABL-2 antibody induce cell death in L1210 cells containing the human IAP gene, respectively.
PP
Figure 4 Shows the results of reducing and non-reducing SDS-PAGE analyses of purified humanized MABL-2 antibody HL5 and sc(Fv)2.
HL5 showed a single band at a position of the molecular weight of a monomer (about 30 kDa) under both conditions, and sc(Fv)2 showed a single band at a position of the molecular weight of a monomer (about 55 kDa) under both conditions.
Cyt
Figure 5 A graph shows the humanized MABL-2 antibody HL5 and sc(Fv)2 and the humanized MABL-1 antibody HL5 and sc(Fv)2 induce cell death in MOLT4 cells.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG, κ
- Specificity
- Human IAP
- Species Reactivity
- Human
- Clone
- MABL-2
- Applications
- ELISA, Cyt, PP
- Related Disease
- Cancers
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The CD47 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Cytotoxicity, Protein Purification.
Target
- Alternative Names
- CD47 Molecule; Antigenic Surface Determinant Protein OA3; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer); Antigen Identified By Monoclonal Antibody 1D8; Leukocyte Surface Antigen CD47; Integrin Associated Protein; Rh-Related Antigen; CD47 Glycoprotein;
- Gene ID
- 961
- UniProt ID
- Q08722
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
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IgM Antibody Products
Single Domain Antibody Products
Non-Human Primate (NHP) Antibody Products
Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-278LC | Human Anti-CD47 Recombinant Antibody (TAB-278LC) | Block, FuncS | Human IgG, κ |
| TAB-279LC | Human Anti-CD47 Recombinant Antibody (TAB-279LC) | Block, FuncS | Human IgG, κ |
| TAB-278LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-278LC-S(P)) | ELISA | Human scFv |
| TAB-279LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-279LC-S(P)) | ELISA | Human scFv |
| TAB-278LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-278LC-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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