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  • Afuco™ Anti-CD79B ADCC Recombinant Antibody (Polatuzumab), ADCC Enhanced

Afuco™ Anti-CD79B ADCC Recombinant Antibody (Polatuzumab), ADCC Enhanced (CAT#: AFC-TAB-897)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human CD79B.


See more Engineered Antibody products for CD79B
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  • Gene Expression
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line REH
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/1889_C4_3_selected.jpg
Figure 2 IHC staining of human lymph node
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra and weak to moderate in reaction center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/ihc_selected.jpg
Figure 3 IHC staining of human lymph node
Figure 3 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows distinct cytoplasmic positivity in cells of the germinal center corona.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9751/ihc_selected.jpg
Normal Tissue
Figure 4 IF staining of human cell line A-431
Figure 4 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to Nucleoplasm &
Plasma membrane & Cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/48_C6_1_blue_red_green.jpg
Figure 5 IF staining of human cell line U-2 OS
Figure 5 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to Nucleoplasm &
Plasma membrane & Cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9178/47_C6_1_blue_red_green.jpg
Figure 6 Colon
Figure 6 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_3.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/44107/169682_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
Figure 8 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007312-CD79B

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Polatuzumab
  • Applications
  • Neut, ELISA, IF, IP, FuncS, FC
  • Conjugate
  • Unconjugated
  • Generic Name
  • Polatuzumab
  • Related Disease
  • Chronic lymphocytic leukemia (CLL)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD79B; CD79b molecule, immunoglobulin-associated beta; CD79B antigen (immunoglobulin associated beta), IGB; B-cell antigen receptor complex-associated protein beta chain; B29; Ig-beta;

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Polatuzumab"

See other products for "CD79B"

Humanized Antibody

CAT Product Name Application Type
TAB-897 Humanized Anti-CD79B Recombinant Antibody (clone Polatuzumab) Neut, ELISA, IF, IP, FuncS, FC, ICC Humanized (from mouse) IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0581 Hi-Affi™ Rabbit Anti-CD79B Recombinant Antibody (clone DS581AB) WB, IHC, ICC, IP, FC Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1918 PE-A*02:01/Human CD79B (LLSAEPVPA) MHC Tetramer FCM

Recombinant Antibody

CAT Product Name Application Type
FAMAB-0058YC Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16) FuncS Hamster IgG
HPAB-0364LY Human Anti-CD79B Recombinant Antibody (HPAB-0364LY) Inhib, ELISA Human IgG
HPAB-618-FY Human Anti-CD79B Recombinant Antibody (HPAB-618-FY) FC, ELISA Human IgG
HPAB-619-FY Human Anti-CD79B Recombinant Antibody (HPAB-619-FY) FC, ELISA Humanized IgG
HPAB-J0057-YC Human Anti-CD79B Recombinant Antibody (HPAB-J0057-YC) ELISA, FC, Inhib, FuncS Humanized IgG1

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0364LY-S(P) Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-0364LY-S(P)) Inhib, ELISA Human scFv
HPAB-618-FY-S(P) Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-618-FY-S(P)) FC, ELISA Humanized scFv
HPAB-619-FY-S(P) Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-619-FY-S(P)) FC, ELISA Humanized scFv
HPAB-N0044-YC-S(P) Human Anti-CD79b Recombinant Antibody; scFv Fragment (HPAB-N0044-YC-S(P)) FuncS Humanized scFv
HPAB-1939-FY-S(P) Human Anti-CD79B Recombinant Antibody (clone huMA79b); scFv Fragment ELISA, FC, FuncS Humanized scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0364LY-F(E) Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-0364LY-F(E)) Inhib, ELISA Human Fab
HPAB-1491-FY-S(P) Human Anti-CD79B Recombinant Antibody (clone P2C2); Fab Fragment ELISA, WB Human Fab
HPAB-J0055-YC-F(E) Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0055-YC-F(E)) ELISA, FC, Inhib, FuncS Humanized Fab
HPAB-J0056-YC-F(E) Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0056-YC-F(E)) ELISA, FC, Inhib, FuncS Humanized Fab
HPAB-J0057-YC-F(E) Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0057-YC-F(E)) ELISA, FC, Inhib, FuncS Humanized Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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