Rat Anti-Cd8a Recombinant Antibody (clone YTS105.18); scFv Fragment
CAT#: HPAB-S0183-YC-S(P)
Unlike YTS156.7, the YTS105.18 epitope is exposed in the pMHCI/CD8αβ complex. The interacting elements between mouse CD8α and the rat antibody YTS105.18 have been identified in the CD8αα/YTS105.18 Fab co-crystal structure. The two potential models for the pMHCI/CD8αβ complex, in which CD8α occupies an α1 or α2 position, respectively, indicate that inhibition of pMHCI/CD8αβ interaction by mAb YTS105.18 would occur only if CD8αβ binds pMHCI with CD8α in the α1 position, whereas YTS105.18 Fab would not block pMHCI/CD8αβ interactions in which CD8α adopts an α2 position.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1373_A3_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1492_D3_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37756/1377_A3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/12/97_A_7_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000153563-CD8A
❮
❯
Specifications
- Host Species
- Rat
- Type
- Rat scFv
- Specificity
- Mouse CD8A
- Species Reactivity
- Mouse
- Clone
- YTS105.18
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for HPAB-S0183-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone YTS105.18"
- CAT
- Product Name
See other products for "Cd8a"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-369-VHH | Recombinant Anti-Mouse Cd8a VHH Single Domain Antibody | IHC, ICC, IP, ChiP, Neut | Llama VHH |
| NABG-041 | Recombinant Anti-Human CD8A VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-428CQ | Mouse Anti-CD8A Recombinant Antibody (clone UCHT4) | FC, IHC-Fr, IHC-P, IP, Separation, Block | Mouse IgG2a, κ |
| NEUT-431CQ | Rat Anti-CD8A Recombinant Antibody (clone 53-6.7) | ICC, IF, FC, IHC-Fr, IP, FuncS, Block | Rat IgG2a, κ |
| NEUT-432CQ | Rat Anti-CD8A Recombinant Antibody (clone MAB0811) | Block, Depletion | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-429CQ | Mouse Anti-CD8A Recombinant Antibody (clone CT-8) | Neut, FC, IHC, IHC-Fr, IHC-P, IP, ICC | Mouse IgG1, κ |
| NEUT-430CQ | Mouse Anti-CD8A Recombinant Antibody (clone LT8) | WB, Neut | Mouse IgG1 |
| NEUT-433CQ | Mouse Anti-CD8A Recombinant Antibody (clone 76-2-11) | Neut, FC, IHC-Fr, IHC-P, IP | Mouse IgG2a, κ |
| NEUT-434CQ | Mouse Anti-Cd8a Recombinant Antibody (clone OX-8) | WB, Neut, FC, IHC, IHC-Fr, IHC-P, IP, CyTOF® | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0582 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS582AB) | IHC | Rabbit IgG |
| MOR-0589 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS589AB) | IHC-P | Rabbit IgG |
| MOR-0590 | Hi-Affi™ Rabbit Anti-CD8A Recombinant Antibody (clone DS590AB), PE | FC | Rabbit IgG |
| MOR-0057-FY | Rabbit Anti-CD8A Recombinant Antibody (clone AFY0028) | ICC, IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0188-CN | Mouse Anti-CD8A Recombinant Antibody (HPAB-0188-CN) | FC | Mouse IgG |
| HPAB-0189-CN | Mouse Anti-CD8A Recombinant Antibody (HPAB-0189-CN) | FC | Mouse IgG |
| MRO-1761-CN | Rabbit Anti-CD8A Polyclonal Antibody (MRO-1761-CN) | WB, IF, IHC, FC | Rabbit IgG |
| FN-073CQ | Mouse Anti-CD8A Recombinant Antibody (clone 2.43) | FC, IP, Depletion | Mouse IgG2b |
| HPAB-S0183-YC | Rat Anti-Cd8a Recombinant Antibody (clone YTS105.18) | ELISA | Rat IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0041-CN | Mouse Anti-CD8A Recombinant Antibody (clone 13C5) | WB, IP, IF | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0009-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody (clone CT8); scFv Fragment | FC | Mouse scFv |
| FAMAB-0010-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody (clone EP72); scFv Fragment | FC | Mouse scFv |
| FAMAB-0011-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody (clone 3-298); scFv Fragment | FC | Mouse scFv |
| FAMAB-0037-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody (clone 6G5); scFv Fragment | WB, IP, IF | Mouse scFv |
| FAMAB-0038-CN-S(P) | Mouse Anti-CD8A Recombinant Antibody (clone 1C9); scFv Fragment | WB, IP, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0009-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody (clone CT8); Fab Fragment | FC | Mouse Fab |
| FAMAB-0010-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody (clone EP72); Fab Fragment | FC | Mouse Fab |
| FAMAB-0011-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody (clone 3-298); Fab Fragment | FC | Mouse Fab |
| FAMAB-0037-CN-F(E) | Mouse Anti-CD8A Recombinant Antibody (clone 6G5); Fab Fragment | WB, IP, IF | Mouse Fab |
| HPAB-0037-YJ-F(E) | Human Anti-CD8A Recombinant Antibody; Fab Fragment (HPAB-0037-YJ-F(E)) | IA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY114 | Mouse Anti-NHP CD8A Recombinant Antibody (clone T8/209) | ELISA | Mouse IgG1, kappa |
| VS-1024-XY112 | Rat Anti-NHP CD8A Recombinant Antibody (clone YTC182.20) | FC | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY78 | CytoStream™ Mouse Anti-CD8A Recombinant Antibody (VS-0225-XY78) | FC | Mouse IgG2a, kappa |
| VS-0225-XY79 | CytoStream™ Mouse Anti-CD8A Recombinant Antibody (clone SK1) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY375 | Anti-CD8A Immunohistochemistry Kit | IHC | |
| VS-0525-XY1238 | Anti-Mouse CD8A Immunohistochemistry Kit | IHC | |
| VS-0525-XY1237 | Anti-Human CD8A Immunohistochemistry Kit | IHC | |
| VS-0525-XY1240 | Anti-Rat CD8A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC377 | Recombinant Anti-CD8A Vesicular Antibody, EV Displayed (VS-0425-YC377) | ELISA, FC, Neut, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, FC, IF, WB
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
