Mouse Anti-CDH17 Recombinant Antibody (HPAB-M0034-YC) (CAT#: HPAB-M0034-YC)
The mouse antibody exhibits specific targeting for E-cadherin 17. This antibody targets the extracellular region of CDH17; when used for therapeutic purposes, it can bind to the intact form or the carboxyl-terminally truncated format of CDH17. Therefore, this antibody could be used to target other cancers in which CDH17 is overexpressed. Internalization of the antibody into human gastric cancer cells indicates that the antibody is a candidate antibody drug.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/1030_A11_3_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/1030_A11_3_selected.jpg
Figure 2 Duodenum
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23614/52777_A_9_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23614/52777_A_9_2_val_selected.jpg
Figure 3 Small intestine
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_6_2.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Paneth cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_6_2.jpg
Figure 4 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_9_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23616/52785_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, OE19, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079112-CDH17
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079112-CDH17
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CDH17
- Species Reactivity
- Human
- Applications
- ELISA, FC, FuncS, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cadherin 17; Intestinal Peptide-Associated Transporter HPT-1; Cadherin 17, LI Cadherin (Liver-Intestine); Liver-Intestine Cadherin; Human Intestinal Peptide-Associated Transporter HPT-1; Human Peptide Transporter 1; HPT-1 Cadherin; Cadherin-16;
- Gene ID
- 1015
- UniProt ID
- Q12864
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
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IgG Antibody Products
ScFv Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1415CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1415CL-F(E)) | ELISA | Mouse Fab |
| TAB-1416CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1416CL-F(E)) | ELISA | Mouse Fab |
| TAB-1417CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1417CL-F(E)) | ELISA | Mouse Fab |
| TAB-1418CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1418CL-F(E)) | ELISA | Mouse Fab |
| TAB-1419CL-F(E) | Mouse Anti-CDH17 Recombinant Antibody; Fab Fragment (TAB-1419CL-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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