Anti-CDK4 Recombinant Soluble TCR (UNC-CDK4-1) (CAT#: scTCR-115ZP-S(P))
Recombinant Human single-chain TCR (scTCR) UNC-CDK4-1 recognizesCDK4 peptide (ALTPVVVTL) in the context of HLA-A*02:01 . The scTCR is responsible for the specificity of T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nucleoli, nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6024/1704_B1_1_cr5811e29350250_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nucleoli, nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6024/1704_B1_1_cr5811e29350250_selected.jpg
Figure 2 IHC staining of human ovary
(Immunohistochemical staining of human ovary shows strong nuclear positivity in ovarian stroma cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_4_7_selected.jpg
(Immunohistochemical staining of human ovary shows strong nuclear positivity in ovarian stroma cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_4_7_selected.jpg
Figure 3 IHC staining of human endometrium
(Immunohistochemical staining of human endometrium shows moderate nuclear positivity in cells in endometrial stroma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69405/163411_B_5_3_selected.jpg
(Immunohistochemical staining of human endometrium shows moderate nuclear positivity in cells in endometrial stroma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69405/163411_B_5_3_selected.jpg
Figure 4 Colon
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Goblet cells Staining: Low Intensity: Moderate Quantity: <25% Mucosal lymphoid cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_7_3.jpg
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Goblet cells Staining: Low Intensity: Moderate Quantity: <25% Mucosal lymphoid cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_7_3.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_5_6.jpg
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_5_6.jpg
Figure 6 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_9_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_9_8.jpg
Figure 7 RNA cell line category: Group enriched (HBEC3-KT, LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135446-CDK4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135446-CDK4
Specifications
- Target
- CDK4
- Species Reactivity
- Human
- Epitope
- ALTPVVVTL
- MHC
- HLA-A*02:01
- Clone
- UNC-CDK4-1
- Type
- Single-Chain TCR
- Related Disease
- Acute myeloid leukemia (AML)
Target
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2055z | Mouse Anti-CDK4 Recombinant Antibody (clone 23A2) | WB, ICC, IF, IHC | Mouse IgG |
| MRO-0339-CN | Mouse Anti-CDK4 Recombinant Antibody (clone 5-C3-G3) | WB, IF, IHC | Mouse IgG2c |
| MRO-0340-CN | Rabbit Anti-CDK4 Recombinant Antibody (clone CBACN-138) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-0341-CN | Rabbit Anti-CDK4 Recombinant Antibody (clone CBACN-139) | WB, IF, IP | Rabbit IgG |
| VS3-QX216 | Mouse Anti-CDK4 Recombinant Antibody (clone 3D12-A7-F11) | WB | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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