Anti-CDK4 Recombinant Soluble TCR (UNC-CDK4-1)
CAT#: scTCR-115ZP-S(P)
Recombinant Human single-chain TCR (scTCR) UNC-CDK4-1 recognizesCDK4 peptide (ALTPVVVTL) in the context of HLA-A*02:01 . The scTCR is responsible for the specificity of T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nucleoli, nuclear membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6024/1704_B1_1_cr5811e29350250_selected.jpg
Normal Tissue
Figure 2 IHC staining of human ovary
Immunohistochemical staining of human ovary shows strong nuclear positivity in ovarian stroma cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_4_7_selected.jpg
Normal Tissue
Figure 3 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows moderate nuclear positivity in cells in endometrial stroma.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69405/163411_B_5_3_selected.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Goblet cells Staining: Low Intensity: Moderate Quantity: <25% Mucosal lymphoid cells Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_5_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13116/163415_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (HBEC3-KT, LHCN-M2, RH-30)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135446-CDK4
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Specifications
- Target
- CDK4
- Species Reactivity
- Human
- Epitope
- ALTPVVVTL
- MHC
- HLA-A*02:01
- Clone
- UNC-CDK4-1
- Type
- Single-Chain TCR
- Related Disease
- Acute myeloid leukemia (AML)
Target
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Downloadable Resources
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COA
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