Rabbit Anti-CFD Recombinant Antibody (clone R09-6A9)
CAT#: VS3-FY1712
This anti-Factor D antibody detected positive in western blot analysis of factor D in Hela lysates. The recombinant monoclonal antibody is used to detect human CFD. Western blot demonstrated that CFD antibody recognized a target protein with a molecular weight of 27 kDa.
Gene Expression
Tested Data
RNA Expression
Figure 1 RNA cell line category: Group enriched (ASC diff, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197766-CFD
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WB
Figure 1 Anti-CFD Antibody (VS3-FY1712) in WB.
The Factor D expression in Hela lysates were detected using the anti-Factor D by western blot assay.
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Specifications
- Immunogen
- Recombinant human factor D protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CFD
- Species Reactivity
- Human
- Clone
- R09-6A9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 27 kDa, while the observed molecular weight stands at 27 kDa.
- Related Disease
- Age-related macular degeneration (AMD); including dry and wet (non-exudative and exudative) forms; choroidal neovascularization (CNV); uveitis; diabetic and other ischemia-related retinopathies; endophthalmitis; and other intraocular neovascular diseases
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Complement Factor D; Properdin Factor D; Adipsin; D Component Of Complement (Adipsin); C3 Convertase Activator; EC 3.4.21.46; PFD
- Gene ID
- 1675
- UniProt ID
- P00746
- Sequence Similarities
- Belongs to the peptidase S1 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Disulfide bond
Zymogen
- Protein Refseq
- NP_001304264.1; NP_001919.2
- Function
- Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| HPAB-0320LY-S(P) | Human Anti-CFD Recombinant Antibody; scFv Fragment (HPAB-0320LY-S(P)) | Inhib | Human scFv |
| HPAB-0321LY-S(P) | Human Anti-CFD Recombinant Antibody; scFv Fragment (HPAB-0321LY-S(P)) | Inhib | Human scFv |
| HPAB-0322LY-S(P) | Human Anti-CFD Recombinant Antibody; scFv Fragment (HPAB-0322LY-S(P)) | Inhib | Human scFv |
| HPAB-0323LY-S(P) | Human Anti-CFD Recombinant Antibody; scFv Fragment (HPAB-0323LY-S(P)) | Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4081 | Hi-Affi™ Rabbit Anti-CFD Recombinant Antibody (clone SI148DS) | WB | Rabbit IgG |
| MOR-4105 | Hi-Affi™ Rabbit Anti-CFD Recombinant Antibody (clone SI176DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0147CQ-F(E) | Human Anti-CFD Recombinant Antibody; Fab Fragment (HPAB-0147CQ-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0148CQ-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0148CQ-F(E)) | ELISA, FC, FuncS | Humanized Fab |
| HPAB-0749YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0749YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0750YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0750YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0751YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0751YY-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0046-YC | Human Anti-CFD Recombinant Antibody (clone AS-01237) | ELISA, Inhib | Humanized IgG |
| HPAB-1492-FY | Human Anti-CFD Recombinant Antibody (clone 238-1) | ELISA | Humanized IgG |
| HPAB-1493-FY | Human Anti-CFD Recombinant Antibody (clone 238-2) | ELISA | Humanized IgG |
| HPAB-0749YY | Human Anti-CFD Recombinant Antibody (HPAB-0749YY) | ELISA | Humanized IgG |
| HPAB-0750YY | Human Anti-CFD Recombinant Antibody (HPAB-0750YY) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY94 | Human Anti-CFD scFv-Fc Chimera (VS-0425-FY94) | Neut, ELISA | Human IgG1, scFv-Fc |
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