Anti-CFD Recombinant Antibody (Lampalizumab)
CAT#: TAB-754
Recombinant humanized (from mouse) antibody Fab fragment expressed in CHO binding to human CFD. Lampalizumab is a humanized monoclonal antibody designed for the treatment of geographic atrophy secondary to age-related macular degeneration.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (ASC diff, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197766-CFD
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- Fab - G1 - kappa
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF, Stim
- CAS
- 1278466-20-8
- Generic Name
- lampalizumab
- MW
- 46.96 kDa
- Related Disease
- Age-related macular degeneration (AMD), neovascular (wet)
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Applications
- Application Notes
- The CFD antibody has been reported in applications of ELISA, IP, FC, FuncS, Neut, IF, Stim.
Target
- Alternative Names
- lampalizumab;1278466-20-8;Anti-Factor D;RG7417;166-32;FCFD4514S;CFD;complement factor D (adipsin);D component of complement (adipsin) , DF, PFD, properdin factor D;complement factor D;ADN;properdin factor D;C3 convertase activator;complement factor D prep
- Gene ID
- 1675
- UniProt ID
- P00746
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reputable company
This product is made by a reliable company that produces high-grade antibodies. Nothing has let us down.
fantastic for research
This antibody solution has proven to be an excellent research tool, offering the specificity and sensitivity required for our in-depth investigations.
Precise measurement
With the help of the antibody product, we can accurately titrate and ascertain the ideal working concentration for various studies.
Q&As
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What steps should I follow to defrost the antibody?
A: Thaw the antibody on ice gradually to preserve stability and functionality.
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Is it possible to aliquot the antibody for multiple uses?
A: The antibody can be saved from deterioration by aliquoting it into smaller volumes and avoiding repeated freeze-thaw cycles.
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What is the optimal pH for storing antibodies?
A: Generally speaking, physiological pH values of 7.2-7.4 are stable for antibodies. Refer to the product information page for specific guidance.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-754, RRID: AB_3112001)
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Biosimilar Overview
Please refer to Lampalizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lampalizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Lampalizumab"
DrugMonitor™ Anti-Lampalizumab Antibody (VS-1224-YC636)Lampalizumab has been studied in clinical trials for treating geographic atrophy. The DrugMonitor™ Anti-Lampalizumab Antibody (VS-1224-YC636) is an anti-drug antibody (ADA) against Lampalizumab. This drug-based antibody is raised in mice immunized with the Lampalizumab. The anti-Lampalizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lampalizumab in samples.
See other products for "CFD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-034 | Recombinant Anti-CHRM2 VHH Single Domain Antibody (PNBL-034) | FACS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-140 | Human Anti-CFD Recombinant Antibody (clone AFD); Fab Fragment | Neut | Human Fab |
| HPAB-0147CQ-S(P) | Human Anti-CFD Recombinant Antibody; scFv Fragment (HPAB-0147CQ-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0148CQ-S(P) | Human Anti-CFD Recombinant Antibody scFv Fragment (HPAB-0148CQ-S(P)) | ELISA, FC, FuncS | Humanized scFv |
| HPAB-0294-FY-S(P) | Mouse Anti-CFD Recombinant Antibody scFv Fragment (HPAB-0294-FY-S(P)) | ELISA, Inhib | Humanized scFv |
| HPAB-1074-FY-F(E) | Mouse Anti-CFD Recombinant Antibody; Fab Fragment (HPAB-1074-FY-F(E)) | ELISA, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4081 | Hi-Affi™ Rabbit Anti-CFD Recombinant Antibody (clone SI148DS) | WB | Rabbit IgG |
| MOR-4105 | Hi-Affi™ Rabbit Anti-CFD Recombinant Antibody (clone SI176DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0320LY | Human Anti-CFD Recombinant Antibody (HPAB-0320LY) | Inhib | Human IgG |
| HPAB-0321LY | Human Anti-CFD Recombinant Antibody (HPAB-0321LY) | Inhib | Human IgG |
| HPAB-0322LY | Human Anti-CFD Recombinant Antibody (HPAB-0322LY) | Inhib | Human IgG |
| HPAB-0323LY | Human Anti-CFD Recombinant Antibody (HPAB-0323LY) | Inhib | Human IgG |
| HPAB-0324LY | Human Anti-CFD Recombinant Antibody (HPAB-0324LY) | Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0749YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0749YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0750YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0750YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0751YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0751YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0752YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0752YY-F(E)) | ELISA | Humanized Fab |
| HPAB-0753YY-F(E) | Human Anti-CFD Recombinant Antibody Fab Fragment (HPAB-0753YY-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY94 | Human Anti-CFD scFv-Fc Chimera (VS-0425-FY94) | Neut, ELISA | Human IgG1, scFv-Fc |
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