Recombinant Humanized Anti-E Protein Antibody (Z7)
CAT#: HPAB-M0259-YC
Provided is a flavivirus humanized monoclonal antibody clone Z7, which have higher ZIKV-E protein-binding capacity. The binding constant of the antibody (Z7) to ZIKV-E is 200pM. The antibody Z7 detects the infection of common flaviviridae viruses: ZIKV, dengue 1-4 type and yellow fever viruses, and has huge application values on clinic detection and fundamental research.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG, λ
- Specificity
- ZIKV
- Species Reactivity
- ZIKV
- Clone
- Z7
- Applications
- Flow Cytometry, Neutralization
Target
- Alternative Names
- Flavivirus Envelope Protein E
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Strong Viral Neutralization
We tested the Anti-E Protein Antibody (Clone Z7) for its ability to neutralize Zika virus in plaque reduction assays. It demonstrated potent neutralizing activity with a very low KD, confirming its high binding capacity. This antibody is an excellent resource for our flavivirus research and epitope mapping studies.
Broad Flavivirus Detection
This humanized monoclonal antibody showed reactivity not only against ZIKV but also other flaviviruses like Dengue and Yellow Fever in our flow cytometry assays. This broad reactivity is extremely useful for our comparative virology studies. The recombinant nature ensures we have a stable supply of this specific clone.
Q&As
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Does this antibody neutralize Zika virus?
A: Yes, this Recombinant Humanized Anti-E Protein Antibody (Clone Z7) has been shown to have high binding capacity for ZIKV-E protein and is validated for Neutralization (Neut) assays against ZIKV and potentially other flaviviruses.
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What is the binding affinity of this antibody?
A: The binding constant (KD) of the antibody Clone Z7 to ZIKV-E protein is reported to be approximately 0.02 nM (20 pM), indicating a very high affinity interaction.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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