Human Anti-EPHA2 Recombinant Antibody (clone TS1); scFv Fragment (CAT#: HPAB-M0069-YC-S(P))
The antibodies are internalizing antibodies that specifically bind to the tumor associated antigen EphA2. TS1 exhibits a significant improvement in thermostability, with a six degree increase in Tm. This clone is appropriate for use, or for additional engineering to improve Protein A binding.
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Custom Production
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human EPHA2
- Species Reactivity
- Human
- Clone
- TS1
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Ephrin Type-A Receptor 2; Soluble EPHA2 Variant 1; Epithelial Cell Kinase;
- Gene ID
- 1969
- UniProt ID
- P29317
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-083 | Human Anti-EPHA2 Recombinant Antibody (clone 1C1); scFv Fragment | ELISA, WB, FuncS | Human scFv |
| HPAB-0164CQ-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone G5); scFv Fragment | ELISA, IF, FC, FuncS, Inter | Humanized scFv |
| HPAB-0165CQ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone B233); scFv Fragment | ELISA, IF, FC, FuncS | Mouse scFv |
| HPAB-0166CQ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone B208); scFv Fragment | ELISA, IF, FC, FuncS | Mouse scFv |
| HPAB-0167CQ-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone 3F2); scFv Fragment | ELISA, IF, FC, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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