This product is a mouse monoclonal antibody that is specific for human GPC3. This antibody can be used in a variety of applications, such as ELISA, WB.
Figure 1 Binding of immunotoxins on G1 cells.
Zhang, Y. F., & Ho, M. (2016). Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma. Scientific reports, 6(1), 1-11.
Figure 2 Cytotoxicity of immunotoxins on G1 cells. IT, immunotoxin.
The numbers in parentheses are EC50 values of immunotoxins in ng/ml.
Zhang, Y. F., & Ho, M. (2016). Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma. Scientific reports, 6(1), 1-11.
Figure 3 Flow cytometry analysis of five selected mouse hybridoma clones (YP6, YP7, YP8, YP9 and YP9.1) (solid lines) and 1G12, a control anti-GPC3 mAb (dotted lines, in the middle) using A431/G1 and Hep3B.
Filled peak: isotype control.
Phung, Y., Gao, W., Man, Y. G., Nagata, S., & Ho, M. (2012, September). High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening. In MAbs (Vol. 4, No. 5, pp. 592-599). Taylor & Francis.
Figure 4 ELISA analysis of five hybridoma clones on recombinant GPC3 proteins.
GPC3: recombinant GPC3-human Fc; GPC3ΔHS: recombinant GPC3 without HS; control: BSA. 1G12: a commercial anti-GPC3 mAb.
Phung, Y., Gao, W., Man, Y. G., Nagata, S., & Ho, M. (2012, September). High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening. In MAbs (Vol. 4, No. 5, pp. 592-599). Taylor & Francis.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-069 | Recombinant Anti-Mouse Gpc3 VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
TAB-416CQ | Anti-Human GPC3 Therapeutic Single Domain Antibody (HN3) | IP, IHC, FuncS, WB, ELISA, Inhib | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H14 | Anti-Human GPC3 Recombinant Antibody (Codrituzumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - kappa |
TAB-160CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-160CT-S(P)) | FC | Humanized scFv |
TAB-161CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-161CT-S(P)) | FC | Humanized scFv |
TAB-162CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-162CT-S(P)) | FC | Humanized scFv |
TAB-163CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-163CT-S(P)) | FC | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G035E | Anti-Gpc3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-157CT | Human Anti-GPC3 Recombinant Antibody (TAB-157CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-158CT | Human Anti-GPC3 Recombinant Antibody (TAB-158CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-157CT-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-157CT-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
TAB-157CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-157CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
TAB-158CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-158CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-167CT | Human Anti-GPC3 Recombinant Antibody (TAB-167CT) | ELISA, FC | Human IgG |
TAB-168CT | Human Anti-GPC3 Recombinant Antibody (TAB-168CT) | ELISA, FC | Human IgG |
TAB-167CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-167CT-F(E)) | ELISA, FC | Human Fab |
TAB-168CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-168CT-F(E)) | ELISA, FC | Human Fab |
TAB-265CQ-F(E) | Anti-Human GPC3 Recombinant Antibody Fab Fragment (MDX-1414) | ELISA, WB, FC, IHC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-263CQ | Anti-Human GPC3 Recombinant Antibody (YP7) | ELISA, Inhib, IHC | |
TAB-263CQ-S(P) | Anti-Human GPC3 Recombinant Antibody scFv Fragment (YP7) | ELISA, WB, FC, IHC | |
TAB-263CQ-F(E) | Anti-Human GPC3 Recombinant Antibody Fab Fragment (YP7) | ELISA, WB, FC, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC033 | PE-A*02:01/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-LC034 | APC-A*02:01/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-LC782 | A*0201/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-YF297 | A*02:01/Human GPC3 (FVGEFFTDV) MHC Monomer | MHC Multimer | |
MHC-YF468 | H-2Kd/Human GPC3 (EYILSLEEL) MHC Pentamer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1486 | Hi-Affi™ Rabbit Anti-GPC3 Recombinant Antibody (clone DS1486AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0553-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone GES1); Fab Fragment | ELISA, FC, IF, IP | Human Fab |
HPAB-0554-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone huG5S1); Fab Fragment | ELISA, FC, IF, IP | Humanized Fab |
HPAB-0556-CN-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0556-CN-F(E)) | ELISA, WB | Human Fab |
HPAB-0558-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0558-CN-F(E)) | ELISA, WB | Mouse Fab |
HPAB-0560-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0560-CN-F(E)) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H14 | Afuco™ Anti-GPC3 ADCC Recombinant Antibody (Codrituzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2309LY-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-2309LY-S(P)) | ELISA | Human scFv |
HPAB-2310LY-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-2310LY-S(P)) | ELISA | Human scFv |
HPAB-2311LY-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-2311LY-S(P)) | ELISA | Human scFv |
HPAB-2312LY-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-2312LY-S(P)) | ELISA | Human scFv |
HPAB-2313LY-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-2313LY-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0689-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0689-WJ) | ELISA, FC, WB | Human IgG |
HPAB-0691-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0691-WJ) | ELISA, FC, WB | Human IgG |
HPAB-0692-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0692-WJ) | ELISA, FC, WB | Human IgG |
FAMAB-0557WJ | Mouse Anti-GPC3 Recombinant Antibody (clone YP9) | ELISA, WB | Mouse IgG1, κ |
FAMAB-0558WJ | Mouse Anti-GPC3 Recombinant Antibody (clone YP9.1) | ELISA, WB | Mouse IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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