Recombinant Anti-HCV Antibody (95-2) (CAT#: HPAB-1179-FY)

This product is a recombinant antibody that recognizes HCV. The monoclonal antibody 95-2 reacts with the epitope of HCV.


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Neut

Figure 1 HCV1 and 95-2 neutralize HCVpp representing a diverse group of HCV genotypes.

Figure 1 HCV1 and 95-2 neutralize HCVpp representing a diverse group of HCV genotypes.

Fivefold dilutions of HuMAbs HCV1 (squares) and 95-2 (diamonds) and an irrelevant HuMAb (negative control; triangles) were incubated for 1 h at room temperature with lentiviral pseudovirus with an engineered luciferase gene.

Broering, T. J., Garrity, K. A., Boatright, N. K., Sloan, S. E., Sandor, F., Thomas, W. D., ... & Babcock, G. J. (2009). Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. Journal of virology, 83(23), 12473-12482.

ELISA

Figure 2 Determination of critical residues required for HCV1 and 95-2 binding.

Figure 2 Determination of critical residues required for HCV1 and 95-2 binding.

Bacterially expressed fusion proteins containing E2 amino acids 412 to 423 with the indicated amino acid mutated to alanine were assayed in ELISA with 0.052 nM HuMAbs HCV1 and 95-2.

Broering, T. J., Garrity, K. A., Boatright, N. K., Sloan, S. E., Sandor, F., Thomas, W. D., ... & Babcock, G. J. (2009). Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. Journal of virology, 83(23), 12473-12482.


Specifications

  • Host Species
  • Human
  • Specificity
  • HCV
  • Species Reactivity
  • HCV
  • Clone
  • 95-2
  • Applications
  • Neut, ELISA

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • The HCV antibody has been reported in applications of Neutralization, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Hepatitis C virus; HCV

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 95-2"

See other products for "HCV"

Single-domain Antibody

CAT Product Name Application Type
NABG-079 Recombinant Anti-HCV VHH Single Domain Antibody ELISA, IHC, FC, FuncS Llama VHH

Mouse Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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