This product is a recombinant antibody that recognizes HCV. The monoclonal antibody 95-2 reacts with the epitope of HCV.
Figure 1 HCV1 and 95-2 neutralize HCVpp representing a diverse group of HCV genotypes.
Fivefold dilutions of HuMAbs HCV1 (squares) and 95-2 (diamonds) and an irrelevant HuMAb (negative control; triangles) were incubated for 1 h at room temperature with lentiviral pseudovirus with an engineered luciferase gene.
Broering, T. J., Garrity, K. A., Boatright, N. K., Sloan, S. E., Sandor, F., Thomas, W. D., ... & Babcock, G. J. (2009). Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. Journal of virology, 83(23), 12473-12482.
Figure 2 Determination of critical residues required for HCV1 and 95-2 binding.
Bacterially expressed fusion proteins containing E2 amino acids 412 to 423 with the indicated amino acid mutated to alanine were assayed in ELISA with 0.052 nM HuMAbs HCV1 and 95-2.
Broering, T. J., Garrity, K. A., Boatright, N. K., Sloan, S. E., Sandor, F., Thomas, W. D., ... & Babcock, G. J. (2009). Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. Journal of virology, 83(23), 12473-12482.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-079 | Recombinant Anti-HCV VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-444-S(P) | Recombinant Human Anti-HCV Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
HPAB-0043LY-S(P) | Mouse Anti-HCV Antibody scFv Fragment (PA-29) | WB | scFv |
HPAB-0232-FY-S(P) | Recombinant Human Anti-HCV Antibody scFv Fragment (TRN1007) | WB, F, N | Human scFv |
HPAB-0802-FY-F(E) | Recombinant Anti-HCV Antibody scFv Fragment (AOT3) | E | |
HPAB-0803-FY-F(E) | Recombinant Anti-HCV Antibody scFv Fragment (C11-3) | E |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-344CL | Human Anti-HCV Recombinant Antibody (TAB-344CL) | FuncS | Human IgG |
PABX-071 | Recombinant Human Anti-HCV Antibody (HC33.4) | WB, ELISA, Neut, FuncS | IgG |
PABX-079 | Recombinant Human Anti-Hepatitis C virus Antibody (AP33) | WB, ELISA, FuncS | IgG |
PABX-071-F (E) | Recombinant Human Anti-HCV Antibody Fab Fragment (HC33.4) | WB, ELISA, Neut, FuncS | Fab |
PABX-079-F (E) | Recombinant Human Anti-Hepatitis C virus Antibody Fab Fragment (AP33) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABZ-057 | Recombinant Mouse Anti-HCV Antibody (19D9D6) | ELISA | IgG |
HPAB-0802-FY | Recombinant Anti-HCV Antibody (AOT3) | E | |
HPAB-0803-FY | Recombinant Anti-HCV Antibody (C11-3) | E | |
FAMAB-0024WJ | Human Anti-HCV Recombinant Antibody (clone B12.F8) | ELISA, IF, IHC, WB | Human IgG |
FAMAB-0025WJ | Human Anti-HCV Recombinant Antibody (clone CM3.B6) | ELISA, IF, IHC, WB, Inhib | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-071-S (P) | Recombinant Human Anti-HCV Antibody scFv Fragment (HC33.4) | WB, ELISA, Neut, FuncS | scFv |
PABX-079-S (P) | Recombinant Human Anti-Hepatitis C virus Antibody scFv Fragment (AP33) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1118LY-F(E) | Humanized Anti-HCV Antibody Fab Fragment (CBL021) | ELISA, FC | |
HPAB-1119LY-F(E) | Humanized Anti-HCV Antibody Fab Fragment (CBL022) | ELISA, FC | |
HPAB-1120LY-F(E) | Humanized Anti-HCV Antibody Fab Fragment (CBL023) | ELISA, FC | |
HPAB-1121LY-F(E) | Humanized Anti-HCV Antibody Fab Fragment (CBL024) | ELISA, FC | |
HPAB-0232-FY-F(E) | Recombinant Human Anti-HCV Antibody Fab Fragment (TRN1007) | WB, F, N | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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