This product is a recombinant human anti-HIV-1 monoclonal antibody. DH288 specifically binds to gp41.
Figure 1 Eleven of fifteen colostrum Env-specific mAbs inhibit epithelial cell binding of the clade C HIV-1 variant MW965.
Epithelial cell binding inhibition was mediated at a high level by the HIV-1 MW965-neutralizing mAbs (red bars), and at a low level by one nonneutralizing gp120 specific mAb (DH390) and gp41 mAb's (DH288 and DH389).
Jeffries, T. L., Sacha, C. R., Pollara, J., Himes, J., Jaeger, F. H., Dennison, S. M., ... & LaBranche, C. (2016). The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells. Mucosal immunology, 9(2), 414-427.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-486 | Recombinant Anti-HIV-1 gp41 Antibody | WB, Dot, FuncS | IgG |
PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
MRO-4074CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone A9); Fab Fragment | ELISA | Human Fab |
MRO-4075CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D11); Fab Fragment | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-025LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG3) | ELISA | Human antibody |
MRO-026LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG1) | ELISA | Human antibody |
MRO-040LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (M66.6) | ELISA | Human antibody |
MRO-074LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (W) | ELISA | Human antibody |
MRO-077LC-S(P) | Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (3D6) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-331 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-331) | Neut | Mouse scFv |
PSBC-332 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10E8v4-5R+100cF); scFv Fragment | Neut | Human scFv |
PSBC-334 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-334) | ELISA, Neut | Mouse scFv |
PSBC-335 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-335) | ELISA, Neut | Mouse scFv |
PSBC-336 | Mouse Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (PSBC-336) | ELISA, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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