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    Anti-Human MDM2 Immunohistochemistry Kit (CAT#: VS-0525-XY4323)

    The MDM2 IHC kit delivers all-in-one reagents for detecting this key regulator of the p53 tumor suppressor pathway. Suitable for paraffin and frozen sections, it supports research on cancer progression, cell cycle control, and tumor suppression with reliable and reproducible staining outcomes.

    Specific Inquiry
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16303/if_selected.jpg
    Figure 2 IF staining of human cell line U-2 OS
    Figure 2 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/79977/1999_F7_3_selected.jpg
    Figure 3 IHC staining of human cerebellum
    Figure 3 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/ihc_selected.jpg
    Figure 4 IHC staining of human ovary
    Figure 4 IHC staining of human ovary
    (Immunohistochemical staining of human ovary shows strong nuclear positivity in ovarian stroma cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16303/37938_A_6_7_selected.jpg
    Figure 5 IHC staining of human placenta
    Figure 5 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/79977/170698_A_2_7_selected.jpg
    Normal Tissue
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_B_8_5.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_9_3.jpg
    Figure 8 Liver
    Figure 8 Liver
    (Cholangiocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Hepatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_8_4.jpg
    Figure 9 Pancreas
    Figure 9 Pancreas
    (Exocrine glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Pancreatic endocrine cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_2_3.jpg
    Figure 10 Kidney
    Figure 10 Kidney
    (Cells in glomeruli
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_8_5.jpg
    Figure 11 Testis
    Figure 11 Testis
    (Pachytene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Peritubular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Round or early spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_5_6.jpg
    Figure 12 Lymph node
    Figure 12 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_9_8.jpg
    RNA Expression
    Figure 13 RNA cell line category: Cell line enhanced (HBEC3-KT, U-698)
    Figure 13 RNA cell line category: Cell line enhanced (HBEC3-KT, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135679-MDM2

    Specifications

    • Application
    • IHC
    • Size
    • 50 Tests
    • Species Reactivity
    • Human, Monkey
    • Target
    • MDM2
    • Primary Antibody
    • Mouse Anti-MDM2 Antibody
    • Secondary Antibody
    • Goat anti-Mouse Antibody, HRP
    • Sample Type
    • FFPE tissue; Frozen section tissue
    • Kit Storage
    • All reagents should be kept at 2-8°C. The kit remains stable for up to 6 months after arrival.

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Downloads

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    Fab Antibody Products ScFv Antibody Products IgG Antibody Products Chicken IgY Antibody Products Rabbit Monoclonal Antibody Products MHC Tetramer Products for Cancer IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-648-F(E) Recombinant Anti-human MDM2 Antibody Fab Fragment WB, FACS, FuncS Fab
    MHH-648-F(E) Recombinant Human Anti-human MDM2 Antibody Fab Fragment ELISA, WB, FC, FuncS Fab

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