Human Anti-ICAM1 Recombinant Antibody (clone Bersanlimab)

Name: Human Anti-ICAM1 Recombinant Antibody (clone Bersanlimab)
SKU: VS-0723-WK48
Rating: 5 (1 reviews)

CAT#: VS-0723-WK48

This product is a human IgG1 antibody that recognizes human ICAM1, a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. Bersanlimab is recommended for flow cytometry (1/100) and ELISA (1/5000-1/10000) assays.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/29_G3_2_selected.jpg

Subcellular Location and Protein Expression Figure 2 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2142/203_G3_1_selected.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of human cell line EFO-21

Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/1937_A10_1_blue_red_green.jpg

Subcellular Location and Protein Expression Figure 4 IF staining of human cell line GAMG

Immunofluorescent staining of human cell line GAMG shows localization to plasma membrane, vesicles, nucleoplasm & centrosome.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/2058_A10_4_blue_red_green.jpg

Normal Tissue Figure 5 Cerebral cortex

Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_B_9_5.jpg

Normal Tissue Figure 6 Lung

Alveolar cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2126/7230_A_3_4.jpg

Normal Tissue Figure 7 Colon

Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_3.jpg

Normal Tissue Figure 8 Kidney

Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_8_5.jpg

Normal Tissue Figure 9 Lymph node

Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4877/13410_A_9_8.jpg

RNA Expression Figure 10 RNA cell line category: Cell line enhanced (HHSteC, Karpas-707, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090339-ICAM1

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Specifications

Immunogen
Recombinant human ICAM1 protein

Host Species
Human

Type
Human IgG1

Specificity
Human ICAM1

Species Reactivity
Human

Clone
Bersanlimab

Applications
ELISA, FC

Conjugate
Unconjugated

Product Property

Clonality
Monoclonal

Purification
Protein A purified

Purity
>95%

Format
Lyophilized

Buffer
Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.

Preservative
No Preservative

Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping
Ice packs

Applications

Application Notes
ELISA: 1/5000-1/10000
Flow Cytometry: 1/100

Target

Alternative Names
ICAM1; BB2; CD54; P3.58

Gene ID
3383

UniProt ID
P05362

Long Name
Intercellular Adhesion Molecule 1

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Related Diseases

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Related Signaling Pathways

TNF Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0723-WK48.pdf

MSDS

MSDS - VS-0723-WK48.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

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