Mouse Anti-ITGA5 Monoclonal Antibody (VS7-0425-WR154) (CAT#: VS7-0425-WR154)
This product is a mouse IgG antibody that binds to human ITGA5. The antibody can be used for WB, IHC-P, IF, FC, and ELISA assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 High expression in placenta
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/ihc_selected.jpg
Figure 2 Low expression in skeletal muscle
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_B_1_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_B_1_6_val_selected.jpg
Figure 3 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows distinct cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9008/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows distinct cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9008/ihc_selected.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_8_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_8_4.jpg
Figure 5 Placenta
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Hofbauer cells Staining: Low Intensity: Moderate Quantity: <25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_3_7.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Hofbauer cells Staining: Low Intensity: Moderate Quantity: <25% Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2642/10675_A_3_7.jpg
Figure 6 RNA cell line category: Cell line enhanced (hTERT-RPE1, HUVEC TERT2, TIME, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000161638-ITGA5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000161638-ITGA5
Specifications
- Immunogen
- Recombinant human ITGA5 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human ITGA5
- Species Reactivity
- Human
- Molecule Class
- Integrin/Cell Adhesion Molecule
- Applications
- WB, IHC-P, IF, FC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Various cancers; Fibrosis; Cardiovascular diseases
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- FNRA; CD49e; VLA-5; VLA5A
- Gene ID
- 3678
- UniProt ID
- P08648
- Long Name
- Integrin Subunit Alpha 5
- Cellular Localization
- Cell junction, Membrane
- Post Translation Modifications
- Proteolytic cleavage by PCSK5 mediates activation of the precursor.
- Protein Refseq
- NP_002196
- Function
- integrin binding; platelet-derived growth factor receptor binding; protein binding; receptor activity; vascular endothelial growth factor receptor 2 binding;
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-077 | Anti-Human Integrin alpha 5 beta 1 Recombinant Antibody (Volociximab) | ELISA, IHC | IgG4 |
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