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    AbPlus™ Anti-JUN Magnetic Beads (CBACN-148) (CAT#: VS-0424-XY164)

    The AbPlus Anti-JUN Magnetic Beads (CBACN-148) is an innovative affinity resin which is bound with anti-JUN specific antibody (CBACN-148). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of JUN protein under native and denaturing conditions.

    Specific Inquiry
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31174/1313_G11_5_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/if_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human small intestine
    Figure 3 IHC staining of human small intestine
    (Immunohistochemical staining of human small intestine shows moderate nuclear positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_6_2_selected.jpg
    Figure 4 IHC staining of human fallopian tube
    Figure 4 IHC staining of human fallopian tube
    (High expression. RNA expression: 314.1 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7780/18871_A_8_7_val_selected.jpg
    Figure 5 IHC staining of human lymph node
    Figure 5 IHC staining of human lymph node
    (Low expression. RNA expression: 52.1 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7780/18871_A_8_8_val_selected.jpg
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_B_7_5.jpg
    Figure 7 Thyroid gland
    Figure 7 Thyroid gland
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_B_2_5.jpg
    Figure 8 Colon
    Figure 8 Colon
    (Glandular cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_9_3.jpg
    Figure 9 Liver
    Figure 9 Liver
    (Hepatocytes
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_7_4.jpg
    Figure 10 Kidney
    Figure 10 Kidney
    (Distal tubules
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Proximal tubules (cell body)
    Staining: Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_8_5.jpg
    Figure 11 Testis
    Figure 11 Testis
    (Sertoli cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_5_6.jpg
    RNA Expression
    Figure 12 RNA cell line category: Cell line enhanced (RH-30)
    Figure 12 RNA cell line category: Cell line enhanced (RH-30)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177606-JUN

    Specifications

    • Applications
    • Immunoprecipitation, Protein Purification
    • Matrix
    • Magrose bead (> 50 μmol/mL gel)
    • Bead Ligand
    • Anti-JUN specific antibody (CBACN-148)
    • Target
    • JUN
    • Immunogen
    • N terminus of human JUN
    • Target Species
    • Human, Mouse, Rat
    • Antibody Clone
    • CBACN-148
    • Bead Capacity
    • 20-30 mg/mL binding antibody
    • Bead size
    • 10-37 μm
    • Stability
    • pH 2-14
    • Format
    • 20% Suspension
    • Buffer
    • PBS, pH 7.4, with 1% BSA
    • Preservative
    • 0.03% Proclin 300
    • Storage
    • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

    Applications

    • Application Notes
    • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

    Target

    • Introduction
    • This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. Diseases associated with JUN include Sarcoma and Pertussis. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.
    • Alternative Names
    • AP1; p39; AP-1; c-Jun

    Related Resources

    • Related Signaling Pathways
    • Related Diseases

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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