AbPlus™ Anti-JUN Magnetic Beads (CBACN-148)
CAT#: VS-0424-XY164
The AbPlus Anti-JUN Magnetic Beads (CBACN-148) is an innovative affinity resin which is bound with anti-JUN specific antibody (CBACN-148). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of JUN protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31174/1313_G11_5_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows moderate nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_6_2_selected.jpg
Normal Tissue
Figure 4 IHC staining of human fallopian tube
High expression. RNA expression: 314.1 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7780/18871_A_8_7_val_selected.jpg
Normal Tissue
Figure 5 IHC staining of human lymph node
Low expression. RNA expression: 52.1 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7780/18871_A_8_8_val_selected.jpg
Normal Tissue
Figure 6 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_B_7_5.jpg
Normal Tissue
Figure 7 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_B_2_5.jpg
Normal Tissue
Figure 8 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_9_3.jpg
Normal Tissue
Figure 9 Liver
Hepatocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_7_4.jpg
Normal Tissue
Figure 10 Kidney
Distal tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_8_5.jpg
Normal Tissue
Figure 11 Testis
Sertoli cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3801/10121_A_5_6.jpg
RNA Expression
Figure 12 RNA cell line category: Cell line enhanced (RH-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177606-JUN
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-JUN specific antibody (CBACN-148)
- Target
- JUN
- Immunogen
- N terminus of human JUN
- Target Species
- Human, Mouse, Rat
- Antibody Clone
- CBACN-148
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. Diseases associated with JUN include Sarcoma and Pertussis. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.
- Alternative Names
- AP1; p39; AP-1; c-Jun
- Gene ID
- 3725
- UniProt ID
- P05412
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Related Signaling Pathways
BCR Signaling Pathway
cAMP Signaling Pathway
NLR Signaling Pathway
TNF Signaling Pathway
Related Diseases
Bladder Cancer
Endometrial Cancer
Non-small Cell Lung Cancer
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "JUN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1499z | Mouse Anti-JUN Recombinant Antibody (clone 23G9) | WB, ELISA, ICC, IF, IHC | Mouse IgG1 |
| VS3-XY951 | Mouse Anti-JUN Recombinant Antibody (clone 4H9) | ELISA, WB, IHC, ICC | Mouse IgG1 |
| VS3-XY952 | Mouse Anti-JUN Recombinant Antibody (clone 5B1) | ELISA, WB, IHC, ICC | Mouse IgG1 |
| VS3-FY784 | Recombinant Rabbit Anti-JUN Antibody (clone R02-1G3) | WB, ICC, IF, IP | Rabbit IgG |
| VS3-FY785 | Recombinant Rabbit Anti-JUN (phospho Ser63) Antibody (clone R07-3G7) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0043MZ | Chicken Anti-AP-1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1902 | Hi-Affi™ Recombinant Rabbit Anti-JUN Monoclonal Antibody (DS1902AB) | IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY126 | Mouse Anti-NHP JUN Recombinant Antibody (clone 5B1) | WB, IHC, IF, ELISA | Mouse IgG1 |
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