Human Anti-L1CAM Recombinant Antibody (clone H2) (CAT#: FAMAB-0192YC)
Provided are antibodies against mouse L1 from a human synthetic phage display library. The antibodies recognized mouse, but not human L1, by enzyme-linked immunosorbent assay, Western blot, and immunofluorescence staining of cultured neurons. Epitope mapping showed reactivity with the fibronectin type III repeats 1–2 of mouse L1. The antibodies stimulated neurite outgrowth from cerebellar dorsal, root ganglion and motor neurons when offered in substrate-coated form in a dose-dependent manner with maximal effects at approximately 32 nM.
Specific Inquiry
IF
Figure 1 Immunofluorescence of cerebellar granule neurons, L1 transfected L929 cells and parental L929 cells with L1 single-chain variable fragment (scFv) antibodies.
Bound scFv antibodies were visualized by using anti-myc antibody 9E10 followed by Cy3-conjugated goat anti-mouse IgG. The left panels (a tog) represent the corresponding phase-contrast micrographs to the right panels.
WB
Figure 2 Mapping of the L1 epitope recognized by the L1 single-chain variable fragment (scFv) antibodies.
The L1 fragments detected by H2.
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG
- Specificity
- Mouse L1CAM
- Species Reactivity
- Mouse
- Clone
- H2
- Applications
- ELISA, IF, WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone H2"
See other products for "L1CAM"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0635CL | Human Anti-L1CAM Recombinant Antibody (TAB-0635CL) | WB, IF, IHC, PK, ELISA, FC | Human antibody |
| TAB-0635CL-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (TAB-0635CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0635CL-F(E) | Human Anti-L1CAM Recombinant Antibody; Fab Fragment (TAB-0635CL-F(E)) | ELISA, FC | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0636CL | Anti-Human L1CAM Recombinant Antibody (L1-9.3) | WB, IHC, ELISA, FC | |
| TAB-0636CL-S(P) | Anti-Human L1CAM Recombinant Antibody scFv Fragment (L1-9.3) | WB, FC | |
| TAB-0636CL-F(E) | Anti-Human L1CAM Recombinant Antibody Fab Fragment (L1-9.3) | WB, FC |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1999 | Hi-Affi™ Recombinant Rabbit Anti-L1CAM Monoclonal Antibody (DS1999AB) | ELISA, WB | IgG |
| MOR-4297 | Hi-Affi™ Recombinant Rabbit Anti-L1CAM Monoclonal Antibody (SI384DS) | FC | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0191YC | Human Anti-L1CAM Recombinant Antibody (clone G6) | ELISA, IF, WB | Human IgG |
| HPAB-0827-CN | Human Anti-L1CAM Recombinant Antibody (HPAB-0827-CN) | WB, ELISA, IHC, FC | Humanized IgG1, κ |
| HPAB-0828-CN | Human Anti-L1CAM Recombinant Antibody (HPAB-0828-CN) | WB, ELISA, IHC, FC | Humanized IgG1, κ |
| HPAB-J0160-YC | Human Anti-L1CAM Recombinant Antibody (clone Ab4) | FC, Inhib, FuncS | Human IgG |
| HPAB-0561-YJ | Mouse Anti-L1CAM Recombinant Antibody (clone A10-A3) | ELISA, FC, FuncS | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0191-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone G6); Fab Fragment | ELISA, IF, WB | Human Fab |
| FAMAB-0192-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone H2); Fab Fragment | ELISA, IF, WB | Human Fab |
| HPAB-J0160-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone Ab4); Fab Fragment | ELISA, FC, WB, FuncS | Human Fab |
| HPAB-0561-YJ-F(E) | Mouse Anti-L1CAM Recombinant Antibody (clone A10-A3); Fab Fragment | ELISA, FC, FuncS | Mouse Fab |
| HPAB-0562-YJ-F(E) | Human Anti-L1CAM Recombinant Antibody (clone cA10-A3); Fab Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0827-CN-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (HPAB-0827-CN-S(P)) | WB, ELISA, IHC, FC | Human scFv |
| HPAB-0828-CN-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (HPAB-0828-CN-S(P)) | WB, ELISA, IHC, FC | Human scFv |
| HPAB-J0160-YC-S(P) | Human Anti-L1CAM Recombinant Antibody (clone Ab4); scFv Fragment | ELISA, FC, WB, FuncS | Human scFv |
| HPAB-0561-YJ-S(P) | Mouse Anti-L1CAM Recombinant Antibody (clone A10-A3); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
| HPAB-0562-YJ-S(P) | Mouse Anti-L1CAM Recombinant Antibody (clone cA10-A3); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0192YC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.