Human Anti-MPL Recombinant Antibody (clone 5E5); Fab Fragment (CAT#: HPAB-S0097-YC-F(E))
The c-mpl agonist antibody is shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, the antibody Fab fragment may be used for treatment of thrombocytopenia.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7619/1825_E1_28_cr5abb7d728bca3_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7619/1825_E1_28_cr5abb7d728bca3_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117400-MPL
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117400-MPL
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human MPL
- Species Reactivity
- Human
- Clone
- 5E5
- Applications
- ELISA, Agonist
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MPL Proto-Oncogene, Thrombopoietin Receptor; Myeloproliferative Leukemia Virus Oncogene; Myeloproliferative Leukemia Protein; Proto-Oncogene C-Mpl; TPO-R; TPOR; Thrombopoietin Receptor
- Gene ID
- 4352
- UniProt ID
- P40238
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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ScFv-Fc Chimera Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2377z | Mouse Anti-MPL Recombinant Antibody (clone 42A11) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| HPAB-1580-FY | Mouse Anti-MPL Recombinant Antibody (HPAB-1580-FY) | WB, FC, ELISA | Mouse IgG |
| HPAB-1581-FY | Mouse Anti-MPL Recombinant Antibody (HPAB-1581-FY) | FC | Mouse IgG |
| HPAB-1582-FY | Mouse Anti-MPL Recombinant Antibody (HPAB-1582-FY) | ELISA | Mouse IgG |
| VS3-XY1093 | Mouse Anti-MPL Recombinant Antibody (clone 1H2) | ELISA, WB, FC | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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