Rabbit Anti-MPL Recombinant Antibody (clone R03-1C9) (CAT#: VS3-FY1910)
This R03-1C9 recombinant monoclonal antibody was developed to recognize human MPL. It cross-reacts with mouse, rat. The binding specificity of the thrombopoietin receptor antibody was determined using western blot analysis of TPOR/MPL in K562, C6 lysates.
Specific Inquiry
WB
Figure 1 Anti-MPL Antibody (VS3-FY1910) in WB.
The TPOR/MPL expression in K562, C6 lysates were detected using the anti-Thrombopoietin Receptor by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human TPOR
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MPL
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R03-1C9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 71 kDa, while the observed molecular weight stands at 85 kDa.
- Related Disease
- Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- MPL Proto-Oncogene, Thrombopoietin Receptor; Myeloproliferative Leukemia Virus Oncogene; Myeloproliferative Leukemia Protein; Proto-Oncogene C-Mpl; TPO-R; TPOR; Thrombopoietin Receptor
- Gene ID
- 4352
- UniProt ID
- P40238
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 1 subfamily.
- Cellular Localization
- Cell membrane, Golgi apparatus, Membrane
- Post Translation Modifications
- Ubiquitination at Lys-553 and Lys-573 targets MPL for degradation by both the lysosomal and proteasomal pathways.
The E3 ubiquitin-protein ligase CBL significantly contributes to this ubiquitination.
- Protein Refseq
- NP_005364.1
- Function
- Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MPL"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2377z | Mouse Anti-MPL Recombinant Antibody (clone 42A11) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| HPAB-S0095-YC | Human Anti-MPL Recombinant Antibody (clone 10F6) | ELISA, Agonist | Human IgG |
| HPAB-S0096-YC | Human Anti-MPL Recombinant Antibody (clone 10D10) | ELISA, Agonist | Human IgG |
| HPAB-S0097-YC | Human Anti-MPL Recombinant Antibody (clone 5E5) | ELISA, Agonist | Human IgG |
| VS3-XY1093 | Mouse Anti-MPL Recombinant Antibody (clone 1H2) | ELISA, WB, FC | Mouse IgG2b |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-155CQ | Human Anti-MPL Recombinant Antibody (TAB-155CQ) | ELISA, FC, FuncS | Human IgG1 |
| TAB-155CQ-S(P) | Human Anti-MPL Recombinant Antibody; scFv Fragment (TAB-155CQ-S(P)) | ELISA, FC, WB | Human scFv |
| TAB-155CQ-F(E) | Human Anti-MPL Recombinant Antibody; Fab Fragment (TAB-155CQ-F(E)) | ELISA, FC, WB | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-156CQ | Anti-Human MPL Recombinant Antibody (TA136) | ELISA, FC | |
| TAB-156CQ-S(P) | Anti-Human MPL Recombinant Antibody scFv Fragment (TA136) | ELISA, FC | |
| TAB-157CQ-S(P) | Anti-Human MPL Recombinant Antibody scFv Fragment (VB22B) | ELISA, FC | |
| TAB-156CQ-F(E) | Anti-Human MPL Recombinant Antibody Fab Fragment (TA136) | ELISA, FC | |
| TAB-157CQ-F(E) | Anti-Human MPL Recombinant Antibody Fab Fragment (VB22B) | ELISA, FC |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2272 | Hi-Affi™ Recombinant Rabbit Anti-MPL Monoclonal Antibody (DS2272AB) | FC, WB | IgG |
Agonistic Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-108LC | Recombinant Human Anti-Human MPL Agonist Antibody (12B5) | FC, FunS, ELISA | Human antibody |
| MOB-109LC | Recombinant Human Anti-Human MPL Agonist Antibody (12D5) | FC, FunS, ELISA | Human antibody |
| MOB-110LC | Recombinant Human Anti-Human MPL Agonist Antibody (12E10) | FC, FunS, ELISA | Human antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566-CN-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0566-CN-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-0567-CN-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0567-CN-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-0411-YC-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-0411-YC-S(P)) | FC, ELISA | Mouse scFv |
| HPAB-0412-YC-S(P) | Human Anti-MPL Recombinant Antibody (clone 7-10G4344uhm); scFv Fragment | FC, FuncS | Human scFv |
| HPAB-S0097-YC-S(P) | Human Anti-MPL Recombinant Antibody (clone 5E5); scFv Fragment | ELISA, Agonist | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1580-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1580-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1581-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1581-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1582-FY-S(P) | Mouse Anti-MPL Recombinant Antibody; scFv Fragment (HPAB-1582-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-S0095-YC-F(E) | Human Anti-MPL Recombinant Antibody (clone 10F6); Fab Fragment | ELISA, Agonist | Human Fab |
| HPAB-S0096-YC-F(E) | Human Anti-MPL Recombinant Antibody (clone 10D10); Fab Fragment | ELISA, Agonist | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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