Afuco™ Anti-NCAM1 ADCC Recombinant Antibody (Lorvotuzumab), ADCC Enhanced (CAT#: AFC-TAB-188)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD56.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/if_selected.jpg
Figure 2 Cerebral cortex
(Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_9_5.jpg
(Neuropil
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_9_5.jpg
Figure 3 Colon
(Peripheral nerve/ganglion
Staining:
High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_A_8_3.jpg
(Peripheral nerve/ganglion
Staining:
High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_A_8_3.jpg
Figure 4 Soft tissue
(Peripheral nerve
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_1_7.jpg
(Peripheral nerve
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39835/100448_B_1_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (HEL, RH-30, SCLC-21H, SH-SY5Y, U-138 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1
Figure 5 RNA cell line category: Cell line enhanced (HEL, RH-30, SCLC-21H, SH-SY5Y, U-138 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000149294-NCAM1
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Lorvotuzumab
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Lorvotuzumab
- Related Disease
- Small cell lung cancers (SCLC)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- NCAM1; neural cell adhesion molecule 1; CD56; NCAM; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal 5.1H11; MSK39;
- Gene ID
- 4684
- UniProt ID
- P13591
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-188 | Humanized Anti-NCAM1 Recombinant Antibody (clone Lorvotuzumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | Humanized (from mouse) IgG1, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L037R | anti-NCAM1 immunotoxin N901 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L037P | anti-NCAM1 immunotoxin N901 (IgG)-PAP | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0287MZ | Recombinant Mouse Anti-Human Neural Cell Adhesion Molecule 1 Antibody (clone 124D4) | IHC | Mouse antibody |
| FN-091CQ | Recombinant Mouse Anti-NCAM1 Antibody (ERIC-1) | ELISA (Cap), IHC-Fr, WB, Dot | Mouse IgG1 |
| FAMAB-1226CQ | Human Anti-NCAM1 Recombinant Antibody (clone NCAM12.19) | ELISA | Human IgG1 |
| ZG-0601F | Mouse Anti-NCAM1 Recombinant Antibody (clone MOC-1) | IHC-P | Mouse IgG1 |
| ZG-0613F | Mouse Anti-NCAM1 Recombinant Antibody (clone RNL-1) | IHC-Fr, EM | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1761CQ | Recombinant Mouse Anti-NCAM1 Antibody (MEM188) | FC, IHC-Fr, ICC, Separation, BL | IgG2a, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4549 | Hi-Affi™ Recombinant Rabbit Anti-NCAM1 Monoclonal Antibody (TH59DS) | WB, IF, ICC, FC | IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-054CN | Mouse Anti-NCAM1 Recombinant Antibody (clone 5A2) | ELISA, WB, IP, FC, FuncS | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-054CN-F(E) | Mouse Anti-NCAM1 Recombinant Antibody (clone 5A2); Fab Fragment | ELISA, WB, IP, FC | Mouse Fab |
| HPAB-0095-FY-F(E) | Human Anti-NCAM1 Recombinant Antibody; Fab Fragment (HPAB-0095-FY-F(E)) | ELISA | Human Fab |
| HPAB-N0187-YC-F(E) | Human Anti-NCAM1 Recombinant Antibody (clone Promiximab); Fab Fragment | ELISA, FC, WB, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-054CN-S(P) | Mouse Anti-NCAM1 Recombinant Antibody (clone 5A2); scFv Fragment | ELISA, WB, IP, FC | Mouse scFv |
| HPAB-0095-FY-S(P) | Human Anti-NCAM1 Recombinant Antibody; scFv Fragment (HPAB-0095-FY-S(P)) | ELISA | Human scFv |
| HPAB-2060LY-S(P) | Mouse Anti-NCAM1 Recombinant Antibody; scFv Fragment (HPAB-2060LY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
| HPAB-N0187-YC-S(P) | Human Anti-NCAM1 Recombinant Antibody (clone Promiximab); scFv Fragment | ELISA, FC, WB, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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