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Afuco™ Anti-NRP1 ADCC Recombinant Antibody (Vesencumab), ADCC Enhanced (CAT#: AFC-TAB-264)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to NRP1. Vesencumab is an immunomodulator designed for the treatment of solid malignancies. It binds to neuropilin 1.


See more Engineered Antibody products for NRP1
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Normal Tissue
Figure 1 IHC staining of human duodenum
Figure 1 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows moderate granular positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_B_9_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30278/64887_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (fHDF/TERT166, hTERT-RPE1, TIME, U-87 MG)
Figure 8 RNA cell line category: Cell line enhanced (fHDF/TERT166, hTERT-RPE1, TIME, U-87 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099250-NRP1

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Vesencumab
  • Applications
  • IP, IF, FuncS, FC, Neut, ELISA
  • Conjugate
  • Unconjugated
  • Generic Name
  • Vesencumab
  • Related Disease
  • Solid tumors

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Vesencumab; 1205533-60-3; Genentech Anti-NRP1; RG7347; MNRP1685A; NRP1; neuropilin 1; neuropilin-1; CD304; NRP; VEGF165R; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; NP1; BDCA4; DKFZp781F1414; DKFZp686A03134;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Vesencumab"

Anti-Human NRP1 Recombinant Antibody (Vesencumab)
Recombinant monoclonal antibody to NRP1. Vesencumab is an immunomodulator designed for the treatment of solid malignancies. It binds to neuropilin 1.

See other products for "NRP1"

Human Antibody

CAT Product Name Application Type
TAB-264 Anti-Human NRP1 Recombinant Antibody (Vesencumab) IP, IF, FuncS, FC, Neut, ELISA, ICC IgG1 - kappa

Recombinant Antibody

CAT Product Name Application Type
PABZ-095 Human Anti-NRP1 Recombinant Antibody Block Human IgG
HPAB-0514-CN Human Anti-NRP1 Recombinant Antibody (HPAB-0514-CN) ELISA, FC, Block Human IgG1
HPAB-0515-CN Human Anti-NRP1 Recombinant Antibody (HPAB-0515-CN) ELISA, FC, Block Human IgG1
MRO-1081-CN Recombinant Rabbit Anti-NRP1 Monoclonal Antibody (CBACN-399) WB, IF, IHC, IP, FC Rabbit IgG
HPAB-1357-FY Human Anti-NRP1 Recombinant Antibody (HPAB-1357-FY) Block, Inhib Human IgG1

Fab Fragment Antibody

CAT Product Name Application Type
PFBZ-095 Human Anti-NRP1 Recombinant Antibody; Fab Fragment Block Human Fab
HPAB-0514-CN-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-0514-CN-F(E)) ELISA, FC, Block Human Fab
HPAB-0515-CN-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-0515-CN-F(E)) ELISA, FC, Block Human Fab
HPAB-N0370-YC-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-N0370-YC-F(E)) ELISA, Inhib Human Fab
HPAB-N0371-YC-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-N0371-YC-F(E)) ELISA, Inhib Human Fab

Mouse Antibody

CAT Product Name Application Type
TAB-589MZ Rabbit Anti-NRP1 Recombinant Antibody (TAB-589MZ) IHC Rabbit IgG1
TAB-590MZ Anti-Human NRP1 Recombinant Antibody (1.004.012) WB
TAB-591MZ Anti-Human NRP1 Recombinant Antibody FC, IP
TAB-589MZ-S(P) Rabbit Anti-NRP1 Recombinant Antibody; scFv Fragment (TAB-589MZ-S(P)) IHC Rabbit scFv
TAB-590MZ-S(P) Anti-Human NRP1 Recombinant Antibody scFv Fragment (1.004.012) WB, IHC

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1791CQ Recombinant Rat Anti-Nrp1 Antibody (CBL881) FC, Neut IgG2
NEUT-1793CQ Recombinant Rat Anti-Nrp1 Antibody (CBL384) CyTOF, FC, Neut IgG2a
NEUT-1794CQ Recombinant Mouse Anti-Nrp1 Antibody (CBL326) BL, FC, CyTOF IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2501 Hi-Affi™ Recombinant Rabbit Anti-NRP1 Monoclonal Antibody (DS2501AB) WB, IHC-P, IP, FC, IHC-Fr IgG

Neuroscience Antibody

CAT Product Name Application Type
NS-055CN Human Anti-NRP1 Recombinant Antibody (NS-055CN) ELISA, IP, IF, SPR Human IgG
NS-056CN Human Anti-NRP1 Recombinant Antibody (NS-056CN) ELISA, IP, IF, SPR Human IgG
NS-057CN Human Anti-NRP1 Recombinant Antibody (NS-057CN) ELISA, IP, IF, SPR Human IgG
NS-055CN-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-055CN-F(E)) ELISA, IP, IF Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
NS-055CN-S(P) Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-055CN-S(P)) ELISA, IP, IF Human scFv
NS-056CN-S(P) Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-056CN-S(P)) ELISA, IP, IF Human scFv
NS-057CN-S(P) Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-057CN-S(P)) ELISA, IP, IF Human scFv
HPAB-N0370-YC-S(P) Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-N0370-YC-S(P)) ELISA, Inhib Human scFv
HPAB-1797-FY-F(E) Human Anti-NRP1 Recombinant Antibody; Fab Fragment (HPAB-1797-FY-F(E)) FC, ELISA Human Fab

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN1093 PE-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer FCM, IHC
MHC-CN1094 APC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer FCM, IHC
MHC-CN1095 FITC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer FCM, IHC
MHC-CN1096 A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer FCM, IHC

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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