FITC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer (CAT#: MHC-CN1095)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• NRP1

• Antigen Species
• Human

• Peptide
• GMLGMVSGL

• Conjugate
• FITC

• Application
• FCM, IHC

• Antigen Introduction
• This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

• Alternative Names
• Neuropilin 1; Vascular Endothelial Cell Growth Factor 165 Receptor; VEGF165R; NRP; Transmembrane Receptor; CD304 Antigen;

• Gene ID
• 8829

• UniProt ID
• O14786

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