Human Anti-NRP1 (clone Vesencumab) scFv-Fc Chimera
CAT#: VS-0325-FY87
The anti-NRP1 scFv-Fc antibody targets neuropilin-1 (NRP1), a receptor involved in angiogenesis, axon guidance, and cancer progression. It can modulate NRP1 signaling, potentially affecting vascular and tumor biology. The scFv-Fc format provides high specificity and prolonged half-life, enhancing its utility in research and therapeutic applications.








Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human NRP1
- Species Reactivity
- Human
- Clone
- Vesencumab
- Applications
- Immunoprecipitation, Immunofluorescence, Flow Cytometry, Neutralization, ELISA, ICC
- Related Disease
- Cancer and neurodegenerative disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Neuropilin 1; Vascular Endothelial Cell Growth Factor 165 Receptor; VEGF165R; NRP; Transmembrane Receptor; CD304 Antigen
- Gene ID
- 8829
- UniProt ID
- O14786
- Long Name
- Neuropilin 1
- Sequence Similarities
- Belongs to the neuropilin family.
- Cellular Localization
- Mitochondrion membrane; Cell membrane; Cytoplasm
- Post Translation Modifications
- Glycosylation at Asn150, Asn261, Asn300, Asn522, Ser612, Thr827, Ser829, Thr830, Asn842, Ser844, and Asn892
Ubiquitination at Lys53 and Lys106
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect NRP1_HUMAN (1557)
Glycosylation from GlyGen 16 sites, 54 N-linked glycans (4 sites), 5 O-linked glycans (8 sites)
- Protein Refseq
- XP_006717584.1; XP_006717585.1; XP_006717587.1; XP_006717588.1; XP_006717589.1
- Function
- NRP1 (Neuropilin 1) is a co-receptor for VEGF and other signaling molecules, playing a crucial role in angiogenesis, axon guidance, and immune responses. It modulates various signaling pathways and is implicated in cancer progression and other diseases.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NRP1"
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-264 | Anti-Human NRP1 Recombinant Antibody (Vesencumab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-095 | Human Anti-NRP1 Recombinant Antibody; Fab Fragment | Block | Human Fab |
NS-056CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-056CN-F(E)) | ELISA, IP, IF | Human Fab |
NS-057CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-057CN-F(E)) | ELISA, IP, IF | Human Fab |
HPAB-0717-FY-S(P) | Mouse Anti-NRP1 Recombinant Antibody (clone AB016); Fab Fragment | FC | Mouse Fab |
HPAB-0721-FY-S(P) | Mouse Anti-NRP1 Recombinant Antibody (clone AB035); Fab Fragment | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-589MZ | Rabbit Anti-NRP1 Recombinant Antibody (TAB-589MZ) | IHC | Rabbit IgG1 |
TAB-590MZ | Anti-Human NRP1 Recombinant Antibody (1.004.012) | WB | |
TAB-591MZ | Anti-Human NRP1 Recombinant Antibody | FC, IP | |
TAB-589MZ-F(E) | Rabbit Anti-NRP1 Recombinant Antibody; Fab Fragment (TAB-589MZ-F(E)) | IHC | Rabbit Fab |
TAB-590MZ-F(E) | Anti-Human NRP1 Recombinant Antibody Fab Fragment (1.004.012) | WB, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1791CQ | Recombinant Rat Anti-Nrp1 Antibody (CBL881) | FC, Neut | IgG2 |
NEUT-1793CQ | Recombinant Rat Anti-Nrp1 Antibody (CBL384) | CyTOF, FC, Neut | IgG2a |
NEUT-1794CQ | Recombinant Mouse Anti-Nrp1 Antibody (CBL326) | BL, FC, CyTOF | IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2501 | Hi-Affi™ Recombinant Rabbit Anti-NRP1 Monoclonal Antibody (DS2501AB) | WB, IHC-P, IP, FC, IHC-Fr | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0514-CN | Human Anti-NRP1 Recombinant Antibody (HPAB-0514-CN) | ELISA, FC, Block | Human IgG1 |
HPAB-0515-CN | Human Anti-NRP1 Recombinant Antibody (HPAB-0515-CN) | ELISA, FC, Block | Human IgG1 |
HPAB-N0370-YC | Human Anti-NRP1 Recombinant Antibody (HPAB-N0370-YC) | ELISA, Inhib | Human IgG4 (S228P) |
HPAB-N0371-YC | Human Anti-NRP1 Recombinant Antibody (HPAB-N0371-YC) | ELISA, Inhib | Human IgG4 (S228P) |
HPAB-N0372-YC | Human Anti-NRP1 Recombinant Antibody (HPAB-N0372-YC) | ELISA, Inhib | Human IgG4 (S228P) |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0514-CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-0514-CN-S(P)) | ELISA, FC, Block | Human scFv |
HPAB-0515-CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (HPAB-0515-CN-S(P)) | ELISA, FC, Block | Human scFv |
NS-055CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-055CN-S(P)) | ELISA, IP, IF | Human scFv |
NS-056CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-056CN-S(P)) | ELISA, IP, IF | Human scFv |
NS-057CN-S(P) | Human Anti-NRP1 Recombinant Antibody; scFv Fragment (NS-057CN-S(P)) | ELISA, IP, IF | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-055CN | Human Anti-NRP1 Recombinant Antibody (NS-055CN) | ELISA, IP, IF, SPR | Human IgG |
NS-056CN | Human Anti-NRP1 Recombinant Antibody (NS-056CN) | ELISA, IP, IF, SPR | Human IgG |
NS-057CN | Human Anti-NRP1 Recombinant Antibody (NS-057CN) | ELISA, IP, IF, SPR | Human IgG |
NS-055CN-F(E) | Human Anti-NRP1 Recombinant Antibody; Fab Fragment (NS-055CN-F(E)) | ELISA, IP, IF | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1080-CN | Recombinant Mouse Anti-NRP1 Monoclonal Antibody (A3-D1) | WB, IF, IHC | Mouse IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-264 | Afuco™ Anti-NRP1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-264) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN1093 | PE-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
MHC-CN1094 | APC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
MHC-CN1095 | FITC-A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC | |
MHC-CN1096 | A*02:01/Human NRP1 (GMLGMVSGL) MHC Tetramer | FCM, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY206 | AbPlus™ Anti-NRP1 Magnetic Beads (VS-0424-XY206) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC189 | Recombinant Anti-NRP1 Vesicular Antibody, EV Displayed (VS-0425-YC189) | ELISA, FC, Neut, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY4987 | Anti-NRP1 Immunohistochemistry Kit | IHC | |
VS-0525-XY4988 | Anti-Rat NRP1 Immunohistochemistry Kit | IHC | |
VS-0525-XY4989 | Anti-Human NRP1 Immunohistochemistry Kit | IHC | |
VS-0525-XY4990 | Anti-Mouse NRP1 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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