Human Anti-NRP1 (clone Vesencumab) scFv-Fc Chimera (CAT#: VS-0325-FY87)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• Human NRP1

• Species Reactivity
• Human

• Clone
• Vesencumab

• Applications
• Immunoprecipitation, Immunofluorescence, Flow Cytometry, Neutralization, ELISA, ICC

• Related Disease
• Cancer and neurodegenerative disease

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• Neuropilin 1; Vascular Endothelial Cell Growth Factor 165 Receptor; VEGF165R; NRP; Transmembrane Receptor; CD304 Antigen

• Gene ID
• 8829

• UniProt ID
• O14786

• Long Name
• Neuropilin 1

• Sequence Similarities
• Belongs to the neuropilin family.

• Cellular Localization
• Mitochondrion membrane; Cell membrane; Cytoplasm

• Post Translation Modifications
• Glycosylation at Asn150, Asn261, Asn300, Asn522, Ser612, Thr827, Ser829, Thr830, Asn842, Ser844, and Asn892
  Ubiquitination at Lys53 and Lys106
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyConnect NRP1_HUMAN (1557)
  Glycosylation from GlyGen 16 sites, 54 N-linked glycans (4 sites), 5 O-linked glycans (8 sites)

• Protein Refseq
• XP_006717584.1; XP_006717585.1; XP_006717587.1; XP_006717588.1; XP_006717589.1

• Function
• NRP1 (Neuropilin 1) is a co-receptor for VEGF and other signaling molecules, playing a crucial role in angiogenesis, axon guidance, and immune responses. It modulates various signaling pathways and is implicated in cancer progression and other diseases.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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