Recombinant Anti-PCSK9 (AA 31-152 x AA 213-219) Biparatopic Antibody, Tandem scFv (Clone 6E2 x Clone 3D5) (CAT#: VS-0525-YC142)

• Host Animal 1
• Mouse

• Host Animal 2
• Mouse

• Specificity
• HumanPCSK9

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Clone 1
• 6E2

• Clone 2
• 3D5

• Epitope 1
• aa 31-152, Prodomain

• Epitope 2
• aa 213-219, TRFHRQ

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Proprotein Convertase Subtilisin/Kexin Type 9

• Introduction
• This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism.

• Alternative Names
• FH3; PC9; FHCL3; NARC1; LDLCQ1; NARC-1; HCHOLA3; proprotein convertase subtilisin/kexin type 9; convertase subtilisin/kexin type 9 preproprotein; neural apoptosis regulated convertase 1; subtilisin/kexin-like protease PC9

• Gene ID
• 255738

• UniProt ID
• Q8NBP7

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