Afuco™ Anti-PCSK9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H10) (CAT#: AFC-TAB-H10)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human PCSK9. It is a monoclonal antibody against PCSK9 designed to reduce LDL cholesterol
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A-431, CACO-2, HaCaT, HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9
Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- PCSK9(proprotein convertase subtilisin/kexin type 9, neural apoptosis-regulated convertase 1, NARC1, NARC-1, proproteine convertase 9, PC9) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Bococizumab
- Related Disease
- Hypercholesterolemia
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- PCSK9; proprotein convertase subtilisin/kexin type 9; HCHOLA3, hypercholesterolemia, autosomal dominant 3; FH3; NARC 1; NARC1; NARC-1; HCHOLA3;
- Gene ID
- 353175
- UniProt ID
- Q8NBP7
Related Resources
Please refer to Bococizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bococizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "bococizumab"
Anti-Human PCSK9 Recombinant Antibody (Bococizumab)Recombinant Humanized (from mouse) antibody to Human PCSK9. Bococizumab (codenamed RN316)is a monoclonal antibody against PCSK9 designed to reduce LDL cholesterol
DrugMonitor™ Anti-Bococizumab Antibody (VS-1224-YC212)Bococizumab has been used in trials for Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia treatment and prevention. The DrugMonitor™ Anti-Bococizumab Antibody (VS-1224-YC212) is an anti-drug antibody (ADA) against Bococizumab. This drug-based antibody is raised in mice immunized with the Bococizumab. The anti-Bococizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bococizumab in samples.
See other products for "PCSK9"
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Human Antibody Products
Humanized Antibody Products
Fab Antibody Products
Mouse Antibody Products
Single Domain Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H31 | Human Anti-PCSK9 Recombinant Antibody (TAB-H31) | FC, IP, ELISA, Neut, FuncS, IF, IHC | Human IgG2, λ |
| TAB-0953CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0953CL-S(P)) | ELISA | Human scFv |
| TAB-0954CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0954CL-S(P)) | WB | Human scFv |
| TAB-0955CL-S(P) | Mouse Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0955CL-S(P)) | WB | Mouse scFv |
| TAB-0959CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0959CL-S(P)) | ELISA, FC | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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