Afuco™ Anti-PCSK9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H10)
CAT#: AFC-TAB-H10
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human PCSK9. It is a monoclonal antibody against PCSK9 designed to reduce LDL cholesterol
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A-431, CACO-2, HaCaT, HeLa, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9
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Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- PCSK9(proprotein convertase subtilisin/kexin type 9, neural apoptosis-regulated convertase 1, NARC1, NARC-1, proproteine convertase 9, PC9) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Bococizumab
- Related Disease
- Hypercholesterolemia
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Bococizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bococizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "bococizumab"
Anti-Human PCSK9 Recombinant Antibody (Bococizumab)Recombinant Humanized (from mouse) antibody to Human PCSK9. Bococizumab (codenamed RN316)is a monoclonal antibody against PCSK9 designed to reduce LDL cholesterol
DrugMonitor™ Anti-Bococizumab Antibody (VS-1224-YC212)Bococizumab has been used in trials for Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia treatment and prevention. The DrugMonitor™ Anti-Bococizumab Antibody (VS-1224-YC212) is an anti-drug antibody (ADA) against Bococizumab. This drug-based antibody is raised in mice immunized with the Bococizumab. The anti-Bococizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bococizumab in samples.
See other products for "PCSK9"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1775z | Mouse Anti-PCSK9 Recombinant Antibody (clone 40B4) | WB, ELISA, IF, IP | Mouse IgG1, κ |
| HPAB-0041-WJ | Mouse Anti-PCSK9 Recombinant Antibody (clone Ab-3D5) | ELISA, WB, Inhib | Mouse IgG, κ |
| HPAB-667-FY | Human Anti-PCSK9 Recombinant Antibody (HPAB-667-FY) | Inhib, SPR, ELISA | Human IgG2 |
| HPAB-668-FY | Human Anti-PCSK9 Recombinant Antibody (HPAB-668-FY) | Inhib, SPR | Human IgG2 |
| HPAB-1373-FY | Human Anti-PCSK9 Recombinant Antibody (HPAB-1373-FY) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-758 | Anti-PCSK9 Recombinant Antibody (Lodelcizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
| TAB-H10 | Anti-Human PCSK9 Recombinant Antibody (Bococizumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG2 - kappa |
| TAB-0957CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (h7F8) | ELISA | Humanized antibody |
| TAB-0958CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (h7F8ml2) | ELISA | Humanized antibody |
| TAB-0957CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (h7F8) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0956CL | Anti-Human PCSK9 Recombinant Antibody (m7F8) | ELISA | |
| TAB-0956CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (m7F8) | ELISA | |
| TAB-0960CL-S(P) | Anti-Human PCSK9 Recombinant Antibody scFv Fragment (Ab1) | ELISA | Rabbit mAb |
| TAB-0956CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (m7F8) | ELISA | |
| TAB-0960CL-F(E) | Anti-Human PCSK9 Recombinant Antibody Fab Fragment (Ab1) | ELISA | Rabbit mAb |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0953CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0953CL-S(P)) | ELISA | Human scFv |
| TAB-0954CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0954CL-S(P)) | WB | Human scFv |
| TAB-0955CL-S(P) | Mouse Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0955CL-S(P)) | WB | Mouse scFv |
| TAB-0959CL-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (TAB-0959CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0953CL-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (TAB-0953CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0080CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (TAB-0080CL-VHH) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0081CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (TAB-0081CL-VHH) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0082CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (TAB-0082CL-VHH) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0083CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (TAB-0083CL-VHH) | FuncS, Inhib, FC, WB | Single domain antibody |
| TAB-0084CL-VHH | Anti-Human PCSK9 VHH Single Domain Antibody (TAB-0084CL-VHH) | FuncS, Inhib, FC, WB | Single domain antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1826CQ | Recombinant Human Anti-PCSK9 Antibody, Unconjugated | Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2618 | Hi-Affi™ Recombinant Rabbit Anti-PCSK9 Monoclonal Antibody (DS2618AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0051-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0051-FY-S(P)) | Inhib | Human scFv |
| HPAB-0141-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody (clone YW508.20.33); scFv Fragment | FuncS, In vivo | Human scFv |
| HPAB-0152-FY-S(P) | Mouse Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0152-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0240-WJ-S(P) | Mouse Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0240-WJ-S(P)) | ELISA | Mouse scFv |
| HPAB-0241-WJ-S(P) | Mouse Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-0241-WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-758 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-758) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H59 | Afuco™ Anti-PCSK9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H59) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-H31 | Afuco™ Anti-PCSK9 Recombinant Antibody (AFC-TAB-H31), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0312-YC-F(E) | Human Anti-PCSK9 Recombinant Antibody; Fab Fragment (HPAB-M0312-YC-F(E)) | ELISA, Block | Humanized Fab |
| HPAB-1376-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-1376-FY-S(P)) | ELISA | Human scFv |
| HPAB-1378-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-1378-FY-S(P)) | ELISA | Human scFv |
| HPAB-1379-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-1379-FY-S(P)) | ELISA | Human scFv |
| HPAB-1380-FY-S(P) | Human Anti-PCSK9 Recombinant Antibody; scFv Fragment (HPAB-1380-FY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY208 | AbPlus™ Anti-PCSK9 Magnetic Beads (VS-0424-XY208) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY208 | Human Anti-PCSK9 scFv-Fc Chimera (VS-0325-FY208) | WB, Block | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5250 | Anti-PCSK9 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC142 | Recombinant Anti-PCSK9 (AA 31-152 x AA 213-219) Biparatopic Antibody, Tandem scFv (Clone 6E2 x Clone 3D5) | ELISA | Tandem scFv |
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