What does this mRNA product encode?

This mRNA encodes a Human antibody (PABS-0236) against the RSV F protein. It contains the mRNA sequences for both the heavy and light chains, enabling the expression of the full antibody.

Why is the RSV F protein a good target?

The RSV fusion protein (F) is highly conserved and essential for infection. Its prefusion conformation is considered the most relevant target for antiviral strategies because it is the fusion-competent form and a primary target for neutralizing activity.

Human Anti-RSV F Antibody (PABS-0236), mRNA

CAT#: PABS-0236-mRNA

This mRNA encodes a Human antibody against RSV F. It contains two mRNAs that encode for the heavy and light chains of the antibody.

Specifications

Host Species
Human

Specificity
RSV F

Species Reactivity
RSV, HMPV

Related Disease
Lower respiratory tract infections

Product Property

Purity
>95%

Storage
Store at -20°C.

Target

Alternative Names
Fusion glycoprotein; F0; F2; F1

UniProt ID
P03420

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Efficient In Vivo Expression

We used this mRNA to express the human anti-RSV F antibody. The expression levels were sufficient for our research needs. It correctly encoded the heavy and light chains, leading to the production of an antibody that recognized the fusion glycoprotein.

Targets RSV Fusion Protein

Our study focuses on the RSV F protein, and this mRNA product provided a novel way to generate the specific antibody (PABS-0236). The resulting antibody showed good specificity for the viral membrane protein, relevant for our antiviral strategy research.

Q&As

What does this mRNA product encode?

A: This mRNA encodes a Human antibody (PABS-0236) against the RSV F protein. It contains the mRNA sequences for both the heavy and light chains, enabling the expression of the full antibody.
Why is the RSV F protein a good target?

A: The RSV fusion protein (F) is highly conserved and essential for infection. Its prefusion conformation is considered the most relevant target for antiviral strategies because it is the fusion-competent form and a primary target for neutralizing activity.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - PABS-0236-mRNA.pdf

MSDS

MSDS - PABS-0236-mRNA.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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