Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) (CAT#: TAB-709)

Recombinant humanized (from mouse) antibody expressed in CHO binding to RSV glycoprotein F. It is a humanized monoclonal antibody for the prevention of respiratory syncytial virus infection in high-risk infants.

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SDS-PAGE

Figure 1 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in SDS-PAGE

Figure 1 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in SDS-PAGE

SDS-PAGE analysis of TAB-709 in non-reduced (Lane 1, 1.5 μg) and β-mercaptoethanol-reduced (Lane 2, 1.5 μg) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different reduced proteins (Heavy chain and Light chain) migrate as about 25 kDa and 50 kDa, respectively.

SEC-HPLC

Figure 2 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in SEC-HPLC

Figure 2 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in SEC-HPLC

The purity of TAB-709 was greater than 95% as determined by SEC-HPLC.

Column: 3 µm, 7.8 x 300 nm
Mobile phase: 150 mM Sodium Phosphate Buffer, pH 7.0
Detection: UV 280 nm
Injection: 10 µl

WB

Figure 3 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in WB

Figure 3 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in WB

Western blot analysis of TAB-709 was performed by loading Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F Protein (His Tag) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-709 and HRP Goat Anti-Human IgG as a secondary antibody. Chemiluminescent detection was performed.
Lane 1: Reduced antigen (1 μg)

DB

Figure 4 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in DB

Figure 4 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in DB

Dot Blot analysis of TAB-709 was performed by coating with Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F Protein (His Tag).

TAB-709 incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-Human IgG as a secondary antibody (1: 2000)

ELISA

Figure 5 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in ELISA

Figure 5 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in ELISA

ELISA analysis of TAB-709 was performed by coating with Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F Protein (His Tag). Then blocked with BSA, and incubated with TAB-709. The HRP-conjugated goat anti-human IgG as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Humanized (from mouse)
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • RSV
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC, WB
  • MW
  • 148 kDa
  • Related Disease
  • Respiratory Syncytial Virus (RSV) disease

Product Property

  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Applications

  • Application Notes
  • The RSV F antibody has been reported in applications of Dot, Neut.

Target

  • Alternative Names
  • Motavizumab;numax;677010-34-3;MEDI-524;F antibody
    Fusion glycoprotein F0;Protein F;RSV Fusion (F) Glycoprotein

Related Resources

  • Biosimilar Overview
  • Citations
Please refer to Motavizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Motavizumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "RSV F"

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CAT Product Name Application Type
TAB-009 Human Anti-RSV Recombinant Antibody (TAB-009) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
MRO-1209LC Anti-HRSV F Recombinant Antibody (MEDI-493) ELISA, Neut, PK Humanized antibody
MRO-1209LC-S(P) Anti-HRSV F Recombinant Antibody scFv Fragment (MEDI-493) ELISA Humanized antibody
MRO-1209LC-F(E) Anti-HRSV F Recombinant Antibody Fab Fragment (MEDI-493) ELISA Humanized antibody

Customer Reviews and Q&As

Customer Review Q&As

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Emily Roberts
Great for RSV Glycoprotein F
The Anti-RSV Glycoprotein F Therapeutic Antibody (NUMAX) has been excellent for our RSV glycoprotein F studies. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
12-Sep-23
Brian Anderson
Effective in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for RSV glycoprotein F is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
21-Oct-22
Jessica Moore
Consistent and High-Quality
This antibody has proven to be consistent and high-quality in our assays. The reproducible results and strong affinity for RSV glycoprotein F have significantly improved our experiments, making it a crucial part of our research toolkit. The consistent performance has greatly enhanced our data quality.
17-May-21

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-709, RRID: AB_3111987)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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