Mouse Anti-RSV F (clone 101F) scFv-Fc Chimera

CAT#: VS-0425-FY106

This fusion protein targets the F protein of Respiratory Syncytial Virus (RSV), a major cause of respiratory infections in infants and young children. By neutralizing the RSV F protein, it can prevent viral entry into host cells, offering a potential therapeutic and prophylactic strategy against RSV infections.

Specifications

  • Immunogen
  • Mice underwent an antigen-specific immune response using a combination of immunopurified RSV virus (Long strain) and purified F protein (derived from the RSV Long strain).
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, scFv-Fc
  • Specificity
  • RSV F
  • Species Reactivity
  • Respiratory Syncytial Virus (RSV)
  • Clone
  • 101F
  • Applications
  • ELISA, Neutralization
  • Related Disease
  • Respiratory Syncytial Virus (RSV)

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • The optimal dilution concentration is determined by the experiment.

Target

  • Alternative Names
  • RSV Fusion Protein; Respiratory Syncytial Virus Fusion Protein
  • Long Name
  • Respiratory Syncytial Virus Fusion Protein
  • Function
  • The RSV F gene encodes the fusion (F) protein of the Respiratory Syncytial Virus (RSV). This protein is a crucial transmembrane glycoprotein located on the viral envelope and plays a vital role in the virus's ability to infect host cells.
    The primary function of the RSV F protein is to mediate the fusion of the viral membrane with the host cell membrane. This fusion process allows the virus to enter the host cell cytoplasm and initiate infection. The F protein undergoes proteolytic cleavage to become active and can also promote the fusion of infected cells with neighboring uninfected cells, leading to the formation of syncytia, a hallmark of RSV infection.
    Furthermore, the RSV F protein is a major target for neutralizing antibodies and is therefore a key antigen in the development of RSV vaccines and antiviral therapies. Its conserved nature across different RSV strains makes it an attractive target for broad protection strategies.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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