Human Anti-RSV F Recombinant Antibody (clone C57) (CAT#: PABS-0157)
This recombinant monoclonal antibody to RSV F is a Human monoclonal antibody that can be used for applications: FC, ELISA. This product can neutralize RSV with approximately one order of magnitude higher potency compared with the clinically used antibody palivizumab, which is similar to the potency of motavizumab.
Specific Inquiry
Figure 11 Assessment of the ability of hFcγRIIB specific mAbs (clones 6G11 and 6G08) to elicit hFcγRIIB ITIM phosphorylation (pFcγRIIB) on isolated hFcγRIIB+/- x mFcγRII-/- splenic B cells. hFcγRIIB and α-Tubulin were used as loading controls; representative blot shown.
Roghanian, A., Teige, I., Mårtensson, L., Cox, K. L., Kovacek, M., Ljungars, A., ... & Cragg, M. S. (2015). Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo. Cancer cell, 27(4), 473-488.
SPR
Figure 1 Profiles of the indicated IGHV3-33-encoded mAbs affinities to NPDP, NVDP, NANP and C-CSP, as measured by SPR.
The corresponding IGKV genes are annotated.
Murugan, R., Scally, S. W., Costa, G., Mustafa, G., Thai, E., Decker, T., ... & Wardemann, H. (2020). Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature medicine, 26(7), 1135-1145.
ITC
Figure 2 Bar graphs indicate affinities of Fabs from the indicated antibodies for NANP3 and for the two NVDP-containing peptides DND (NVDPNANPNVDP) and NDN (NANPNVDPNANP), measured by isothermal titration calorimetry.
Symbols indicate independent measurements. Means and s.e.m. are shown.
Murugan, R., Scally, S. W., Costa, G., Mustafa, G., Thai, E., Decker, T., ... & Wardemann, H. (2020). Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature medicine, 26(7), 1135-1145.
ITC
Figure 3 Isothermal titration calorimetry (ITC) measurements of IGHV3-33-encoded antibodies binding to NANP3 (mAb 2541)
Murugan, R., Scally, S. W., Costa, G., Mustafa, G., Thai, E., Decker, T., ... & Wardemann, H. (2020). Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature medicine, 26(7), 1135-1145.
Specifications
- Host Species
- Human
- Derivation
- Single B cell sorting
- Type
- Human IgG
- Specificity
- RSV F
- Species Reactivity
- RSV
- Clone
- C57
- Applications
- FC, ELISA
- Related Disease
- Lower respiratory tract infections
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RSV F"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009 | Anti-RSV Recombinant Antibody (Palivizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-709 | Anti-RSV glycoprotein F Recombinant Antibody (Motavizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| MRO-1209LC | Anti-HRSV F Recombinant Antibody (MEDI-493) | ELISA, Neut, PK | Humanized antibody |
| MRO-1209LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (MEDI-493) | ELISA | Humanized antibody |
| MRO-1209LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (MEDI-493) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-365CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-365CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-366CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-366CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-367CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-367CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-368CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-368CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-369CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-369CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC | Human Anti-RSV F Recombinant Antibody (MRO-878LC) | ELISA, Neut | Human IgG |
| HPAB-0293CQ | Human Anti-RSV F Recombinant Antibody (HPAB-0293CQ) | ELISA, Neut, FuncS | Human IgG1 |
| PABC-494 | Recombinant Human Anti-RSV F Antibody (14N4) | SPR, ELISA, Neut | Human IgG1, κ |
| PABS-0236 | Human Anti-RSV F Recombinant Antibody (clone MPE8) | BLI, Neut, Block, ELISA | Human IgG |
| PABJ-0100 | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6) | ELISA, Neut | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (MRO-878LC-S(P)) | ELISA, Neut | Human scFv |
| PSBC-276 | Recombinant Mouse Anti-RSV F Antibody scFv Fragment (5C4) | ELISA, Neut | Mouse scFv |
| HPAB-0105-WJ-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (HPAB-0105-WJ-S(P)) | ELISA, WB | Human scFv |
| PABJ-0100-S(P) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); scFv Fragment | ELISA, Neut | Mouse scFv |
| PABJ-0166-S(P) | Human Anti-RSV F Recombinant Antibody (clone RSD5); scFv Fragment | ELISA, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC-F(E) | Human Anti-RSV F Recombinant Antibody; Fab Fragment (MRO-878LC-F(E)) | ELISA, Neut | Human Fab |
| PFBC-276 | Recombinant Mouse Anti-RSV F Antibody Fab Fragment (5C4) | ELISA, Neut | Mouse Fab |
| PFBC-494 | Recombinant Human Anti-RSV F Antibody Fab Fragment (14N4) | ELISA, Neut | Human Fab |
| PABJ-0100-F(E) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); Fab fragment | ELISA, Neut | Mouse Fab |
| PABJ-0166-F(E) | Human Anti-RSV F Recombinant Antibody (clone RSD5); Fab Fragment | ELISA, Neut | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1210LC | Anti-HRSV F Recombinant Antibody (C11) | ELISA | Mouse Antibody |
| MRO-1211LC | Anti-HRSV F Recombinant Antibody (C13) | ELISA | Mouse Antibody |
| MRO-1210LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (C11) | ELISA | Mouse Antibody |
| MRO-1210LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C11) | ELISA | Mouse Antibody |
| MRO-1211LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C13) | ELISA | Mouse Antibody |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-009 | Afuco™ Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-709 | Afuco™ Anti-RSV F ADCC Recombinant Antibody (Motavizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YC250 | H-2Kd/Respiratory syncytial virus Fusion protein (F) (KYKNAVTEL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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