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    Human Anti-RSV F Recombinant Antibody (VS-0326-FY233)

    CAT#: VS-0326-FY233

    This is a recombinant human IgG1 monoclonal antibody specifically engineered to target the Fusion (F) protein of the Respiratory Syncytial Virus (RSV), specifically the RSV-A subtype.

    Sub Cat Clone Affinity Constant Epitope Size Conjugation Endotoxin Purity Fc Engineering  
    VS-0326-FY269 3301 The affinity is approximately 4.5 nM. Antigenic Site I (Buries 715 Ų; contacts α8 helix and curved β-sheet, bridges Site IV)
    VS-0326-FY270 2245 The affinity is approximately 150 nM. Antigenic Site V (Buries 850 Ų; contacts β3-β4 hairpin, Site II α6/α7 helices)
    More Infomation

    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1
    • Antibody Isotype
    • IgG1
    • Species Reactivity
    • Respiratory Syncytial Virus (RSV)-A
    • Applications
    • Neutralization, Enzyme-linked Immunosorbent Assay
    • Related Disease
    • Respiratory syncytial virus infection

    Product Property

    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • RSV-F, Fusion Glycoprotein
    • Long Name
    • Respiratory Syncytial Virus Fusion Protein
    • Function
    • The RSV F gene encodes the fusion (F) protein of the Respiratory Syncytial Virus (RSV). This protein is a crucial transmembrane glycoprotein located on the viral envelope and plays a vital role in the virus's ability to infect host cells.
      The primary function of the RSV F protein is to mediate the fusion of the viral membrane with the host cell membrane. This fusion process allows the virus to enter the host cell cytoplasm and initiate infection. The F protein undergoes proteolytic cleavage to become active and can also promote the fusion of infected cells with neighboring uninfected cells, leading to the formation of syncytia, a hallmark of RSV infection.
      Furthermore, the RSV F protein is a major target for neutralizing antibodies and is therefore a key antigen in the development of RSV vaccines and antiviral therapies. Its conserved nature across different RSV strains makes it an attractive target for broad protection strategies.
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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS-0326-FY233.pdf

    MSDS

    MSDS - VS-0326-FY233.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Isotype Control

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

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