Anti-SDC1 Antibody-Cytokine Fusion Protein, IgG (B-B4)-IFNα2 (CAT#: VS-0624-FY78)

• Target
• CD138

• Molecule Class
• IgG-IFNα2

• Species Reactivity
• Human

• Expression Host
• CHO

• Clone
• B-B4

• Related Disease
• Monoclonal Gammopathy Of Uncertain Significance and Endometritis

• Cytokine 1
• IFNα2

• Cytokines 1 Description
• IFNα2 is a protein secreted by cells infected with viruses, where it acts on other cells to inhibit viral infection. There are 3 types of interferons: interferon type I, interferon type II, and interferon type III. Type II interferons, also known as IFNγ, are produced by specific cells of the immune system. Unlike type I and type III interferons, IFNγ plays only a modest role in directly limiting viral infection. Type I and type III interferons act similarly. However, the effects of type III interferons (also known as IFNλ) are limited to epithelial cells, whereas type I interferons act on all cells of the body.

• Cytokine 1 Species
• Human

• Applications
• This product is for immuno therapy research. It can be used therapeutically to deliver biologically active ligands to a desired tissue.

• Introduction
• The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

• Alternative Names
• Syndecan 1; Syndecan Proteoglycan 1; CD138 Antigen; SYND1; SDC; Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor; Syndecan-1; Syndecan; CD138; Anti-CD138-IFNα2

• Gene ID
• 6382

• UniProt ID
• P18827

• VS-0624-FY79
• Anti-SDC1 Antibody-Cytokine Fusion Protein, IgG (B-B4)-IFNα2^YNS

• VS-0624-FY80
• Anti-SDC1 Antibody-Cytokine Fusion Protein, IgG (B-B4)-IFNα14

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